High purity antineoplastic agent Capecitabine with best quality

Product Name:

Capecitabine

Synonyms:

5'-DEOXY-5-FLUOROCYTISINE;5'-DEOXY-5-FLUORO-N-[(PENTYLOXY)CARBONYL]CYTIDINE;CAPECITABINE;RO-9-1978;pentyl [1-(3,4-dihydroxy-5-methyl-oxolan-2-yl)-5-fluoro-2-oxo-pyrimidin-4-yl]aminoformate;XELODA;Cpecitabine;5Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine, Ro-9-1978, Xeloda

CAS:

154361-50-9

MF:

C15H22FN3O6

MW:

359.35

Product Categories:

Active Pharmaceutical Ingredients;Antineoplastic;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Antineoplastic drug, 5-FU analog;Anti-cancer;API;XELODA;Cardiovascular Drugs;Inhibitors

Mol File:

154361-50-9.mol

Chemical Properties

melting point 

110-121°C

density 

1.49 g/cm3

storage temp. 

-20°C Freezer

water 

≤ 0.3%

specific rotation 

+96.0 ~+100.0

Usage And Synthesis

Interactions

No clinical side effect has been seen when it is used in combination with drugs such as antihistamines, NSAIDs, morphine, acetaminophen, aspirin, anti-nausea drugs, H2 receptor antagonist etc. 
The serum protein binding of Capecitabine is relatively low (64%); the possibility of binding with drugs that bind tightly to protein through replacement is still unpredictable.
Interaction with cytochrome P450 emsyme: no influence of Capecitabine on human liver microsome P450 enzyme is found in vitro.
The dose may need to be reduced when any drug among phenytoin and coumarin derivative-type anticoagulants is used in combination with Rhoda.

Chemical Properties

Colourless solid

Usage

An antineoplastic agent. A prodrug of doxifluridine.

Capecitabine is an antineoplastic agent. Capecitabine is a prodrug of Doxifluridine (D556750).

An antiproliferative 5-fluorouracil releasing compound