6627-53-8 Benzene,...

6627-53-8 Benzene,4-chloro-2-methoxy-1-nitro-

6627-53-8 Benzene,4-chloro-2-methoxy-1-nitro-

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Keywords

Benzene,4-chloro-2-methoxy-1-nitro- 6627-53-8 6627-53-8

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  • Appearance:white powder
  • Application:Organic Chemicals
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  • ProductionCapacity:1|Metric Ton|Day
  • Storage:2-6℃
  • Transportation:by air

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Details:

5-CHLORO-2-NITROANISOLE Basic information
Product Name: 5-CHLORO-2-NITROANISOLE
Synonyms: 5-CHLORO-2-NITROANISOLE;4-CHLORO-2-METHOXYNITROBENZENE;4-chloro-2-methoxy-1-nitro-benzen;4-Chloro-2-methoxynitrobenzene 98%;4-chloro-2-methoxy-1-nitro-benzene;4-Chloro-3-methoxy-1-nitrobenzene;5-CHLORO-2-NITROANISOLE 97%;5-Chloro-2-nitroanisole,97%
CAS: 6627-53-8
MF: C7H6ClNO3
MW: 187.58
EINECS: 229-594-1
Product Categories: blocks;NitroCompounds;Miscellaneous;Anisole;Nitro Compounds;Nitrogen Compounds;Organic Building Blocks;Building Blocks;Chemical Synthesis;Nitro Compounds;Nitrogen Compounds;Organic Building Blocks
Mol File: 6627-53-8.mol
5-CHLORO-2-NITROANISOLE Structure
 
5-CHLORO-2-NITROANISOLE Chemical Properties
Melting point  70-72 °C(lit.)
CAS DataBase Reference 6627-53-8(CAS DataBase Reference)
EPA Substance Registry System Benzene, 4-chloro-2-methoxy-1-nitro- (6627-53-8)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-36
WGK Germany  3
MSDS Information
Provider Language
SigmaAldrich English
 
5-CHLORO-2-NITROANISOLE Usage And Synthesis
Chemical Properties SLIGHTLY YELLOW TO GREEN CRYSTALLINE POWDER
Usage 5-Chloro-2-nitroanisole is involved in the synthesis of orally bioavailable anaplastic lymphoma kinases (ALK) inhibitors as anticancer drugs. In addition it is used in the synthesis of kinesin spindle protein (KSP) inhibitors which are responsible for the spindle pole separation which occurs during mitosis in cancer cells.
 
5-CHLORO-2-NITROANISOLE Preparation Products And Raw materials
Raw materials Sodium bisulfite-->Cupric sulfate-->2-Methoxy-4-nitroaniline-->2-CHLORO-5-NITROANISOLE

 

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