89-57-6

Details:

5-Aminosalicylic acid Basic information
Product Name: 5-Aminosalicylic acid
Synonyms: LABOTEST-BB LT00134704;IFLAB-BB F1918-0003;BENZOIC ACID, 5-AMINO-2-HYDROXY-;M-AMINOSALICYLIC ACID;MESALAMINE;MESALAZINE;2-HYDROXY-5-AMINOBENZOIC ACID;3-Carboxy-4-hydroxyaniline
CAS: 89-57-6
MF: C7H7NO3
MW: 153.14
EINECS: 201-919-1
Product Categories: FINE Chemical & INTERMEDIATES;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Carboxylic Acids;Phenyls & Phenyl-Het;Organic acids;Various Metabolites and Impurities;Fendosal;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Carboxylic Acids;Phenyls & Phenyl-Het;Aromatics;API;CITANEST;Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File: 89-57-6.mol
5-Aminosalicylic acid Structure
5-Aminosalicylic acid Chemical Properties
Melting point  275-280 °C (dec.)(lit.)
Fp  279-281°C
storage temp.  2-8°C
form  tablets
color  off-white to gray
Water Solubility  <0.1 g/100 mL at 21 ºC
Decomposition  279-281 ºC
Merck  14,5904
BRN  2090421
Stability: Stable. Incompatible with acids, acid anhydrides, acid chlorides, chloroformates, strong oxidizing agents.
CAS DataBase Reference 89-57-6(CAS DataBase Reference)
NIST Chemistry Reference Mesalamine(89-57-6)
EPA Substance Registry System Benzoic acid, 5-amino-2-hydroxy-(89-57-6)
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-24/25
WGK Germany  2
RTECS  VO1400000
F  8-10-23
Hazard Note  Irritant
HazardClass  IRRITANT
HS Code  29225000
Hazardous Substances Data 89-57-6(Hazardous Substances Data)
MSDS Information
Provider Language
3-Carboxy-4-hydroxyaniline English
SigmaAldrich English
ACROS English
ALFA English
5-Aminosalicylic acid Usage And Synthesis
Chemical Properties Off-White Crystals
Usage The active metabolite of Sulfasalazine. Anti-inflammatory (gastrointestinal)
Usage The active metabolite of Sulfasalazine (S699084). Anti-inflammatory (gastrointestinal).
Usage anesthetic (local)
Usage peroxidase substrate
Usage For the treatment of active ulcerative proctitis.
General Description Odorless white to pinkish crystals or purplish-tan powder. Aqueous solutions acidic (pH approximately 4.1 at 0.8 mg/L water) .
Air & Water Reactions Sensitive to moisture. Water insoluble.
Reactivity Profile 5-Aminosalicylic acid is incompatible with acids, acid chlorides, acid anhydrides, chloroformates and strong oxidizers.
Fire Hazard Flash point data for 5-Aminosalicylic acid are not available; however, 5-Aminosalicylic acid is probably combustible.
5-Aminosalicylic acid Preparation Products And Raw materials
Raw materials Sodium carbonate-->ZINC-->Water-->Sodium dithionite-->Methanesulfonyl chloride-->Salicylic acid-->Tyramine-->5-Nitrosalicylic acid
Preparation Products Benzoic acid, 2-[[1-amino-7-[[4-[[6-amino-5-[(3-carboxy-4-hydroxyphenyl)azo]-1-hydroxy-3-sulfo-2-naphthalenyl]azo]-2-methoxyphenyl]azo]-8-hydroxy-3,6-disulfo-2-naphthalenyl]azo]-5-[[6-amino-5-[(3-carboxy-4-hydroxyphenyl)azo]-1-hydroxy-3-sul
Tag:5-Aminosalicylic acid(89-57-6) Related Product Information
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