88-69-7

Details:

2-Isopropylphenol Basic information
Product Name: 2-Isopropylphenol
Synonyms: 1-Hydroxy-2-isopropylbenzene;2-(1-methylethyl)-pheno;2-(1-Methylethyl)phenol;2-(1-methylethyl)-Phenol;Isopropylphenol, ortho;o-Hydroxycumene;o-isopropyl-pheno;Phenol, o-isopropyl-
CAS: 88-69-7
MF: C9H12O
MW: 136.19
EINECS: 201-852-8
Product Categories: API intermediates;Alphabetical Listings;Flavors and Fragrances;I-L;Organic Building Blocks;Oxygen Compounds;Phenols;Aromatics;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File: 88-69-7.mol
2-Isopropylphenol Structure
2-Isopropylphenol Chemical Properties
mp  12-16 °C(lit.)
bp  212-213 °C(lit.)
density  1.012 g/mL at 25 °C(lit.)
vapor pressure  <0.05 mm Hg ( 25 °C)
FEMA  3461
refractive index  n20/D 1.526(lit.)
Fp  192 °F
solubility  insoluble
Water Solubility  insoluble
BRN  1363322
CAS DataBase Reference 88-69-7(CAS DataBase Reference)
NIST Chemistry Reference Phenol, 2-(1-methylethyl)-(88-69-7)
EPA Substance Registry System Phenol, 2-(1-methylethyl)-(88-69-7)
Safety Information
Hazard Codes  C,Xn
Risk Statements  34-22
Safety Statements  26-36/37/39-45-28
RIDADR  UN 3145 8/PG 2
WGK Germany  3
RTECS  SL5900000
HazardClass  8
PackingGroup  II
HS Code  29071900
MSDS Information
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2-Isopropylphenol Usage And Synthesis
Chemical Properties CLEAR SLIGHTLY YELLOW LIQUID
Usage 2-Isopropylphenol is an impurity of Propofol (P829750).
General Description Light-yellow liquid. Less dense than water and insoluble in water. Hence floats on water.
Air & Water Reactions Insoluble in water.
Reactivity Profile Phenols, such as 2-Isopropylphenol, do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has Ka = 1.3 x 10^[-10]). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases. Such heating may initiate polymerization of the organic compound. Phenols are sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid. Nitrated phenols often explode when heated. Special Hazards of Combustion Products: Irritating vapors and toxic gases, such as carbon dioxide and carbon monoxide, may be formed when involved in fire [USCG, 1999].
Health Hazard Exposure can cause irritation of eyes, nose and throat.
Fire Hazard Special Hazards of Combustion Products: Irritating vapors and toxic gases, such as carbon dioxide and carbon monoxide, may be formed when involved in fire.
2-Isopropylphenol Preparation Products And Raw materials
Raw materials Alkyl phenol-->Propofol
Preparation Products Propoxur-->2,3-Dihydro-2,2-dimethyl-7-benzofuranol -->Isoprocarb-->2-ISOPROPYLANISOLE