Butanoic acid, 2-me...

Butanoic acid, 2-methyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrah 75330-75-5

Butanoic acid, 2-methyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrah 75330-75-5

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Butanoic acid, 2-methyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrah 75330-75-5 High quality

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Details:

Lovastatin Basic information
a cholesterol lowering agent General description Structure of statin compound Active Mechanism Medicinal Value Biosynthesis Uses Metabolism Precautions Adverse reaction Chemical property Uses Production method
Product Name: Lovastatin
Synonyms: Lovastatin (Simvastatin EP Impurity E);Lovastatin - CAS 75330-75-5 - Calbiochem;8-[2-(4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-naphth;Mevinolin, 6-alpha-Methylcompactin;Mevinolin, Monacolin K, L 154803, MB 530B, MSD 803;Lovastatin (Mevacor);(2S)-2-methyl-butanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester;Lovastatin for peak identification
CAS: 75330-75-5
MF: C24H36O5
MW: 404.54
EINECS: 616-212-7
Product Categories: pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Isotopically Labeled Pharmaceutical Reference Standard;RYTHYMOL;antibiotic;Cardiovascular APIs;Inhibitors;Antibiotics;APIs;Intermediates & Fine Chemicals;Pharmaceuticals;API's;HMG-CoA reductase;Chiral Reagents;chemical reagent;Heterocycles;Inhibitor
Mol File: 75330-75-5.mol
Lovastatin Structure
Lovastatin Chemical Properties
Melting point 175°C
alpha D25 +323° (c = 0.5 g in 100 ml acetonitrile)
Boiling point 559.2±50.0 °C(Predicted)
density 1.12±0.1 g/cm3(Predicted)
refractive index 320 ° (C=0.5, CH3CN)
storage temp. 2-8°C
solubility ethanol: soluble9.80-10.20mg/mL, clear, colorless to faintly yellow
form White to off-white powder
pka 13.49±0.40(Predicted)
Water Solubility 0.0004 mg/mL at 25 ºC
Merck 14,5586
CAS DataBase Reference 75330-75-5(CAS DataBase Reference)
EPA Substance Registry System Lovastatin (75330-75-5)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-36/37/39-26
RIDADR 3077
WGK Germany 3
RTECS EK7907000
HazardClass 9
PackingGroup III
HS Code 29322090
Hazardous Substances Data 75330-75-5(Hazardous Substances Data)
Toxicity LD50 orally in mice: >1000 mg/kg (Endo)

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