INCB 024360

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0 Metric Ton	Negotiable

0 Metric Ton

Negotiable

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Min.Order :0 Metric Ton
Purity: 98

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1204669-58-8 INCB 024360 99%

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NCB 024360 is a potent and novel indoleamine-2,3 dioxygenase (IDO)inhibitor with an IC 50 value <100 nM.
IC50 Value: <100 nM [1]
Target: Indoleamine-2,3-dioxygenase
IDO is an immunomodulatory enzyme produced by some alternatively activated macrophages and other immunoregulatory cells (also used as an immune subversion strategy by many tumors). Interferon-gamma has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as Toxoplasma and chlamydia, at least partly because of the induction of indoleamine 2,3-dioxygenase.

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