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Menadione supplier 99% china GMP

Menadione supplier 99% china GMP

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0 Metric Ton

Negotiable

  • Min.Order :0 Metric Ton
  • Purity: 99%

Keywords

Menadione supplier Menadione GMP Menadione 99%

Quick Details

  • Appearance:Powder
  • Application:Pharm, Food, Nutrition, Health Products
  • PackAge:25kg/drum
  • ProductionCapacity:|Metric Ton|Day
  • Storage:Store in dry places and keep away from strong direct light and heat.
  • Transportation:transport as the regulation of chemicals

Superiority:

1.USP/EP/BP/FCC/CP 2.GMP/DMF/KOSHER/HALAL/HACCP 3.10 Years Experience 4.Delivery within 5 days 5.OEM ability …

Details:

1.USP/EP/BP/FCC/CP
2.GMP/DMF/KOSHER/HALAL/HACCP
3.10 Years Experience
4.Delivery within 5 days
5.OEM ability

 

 

1. Introduction of Menadione

 


Our Menadione products are mainly Menadione 99%. As one kind of bright yellow crystals, this chemical could be stored in dry places. Our products package is 25kg/drum. For being incompatible with strong oxidizing agents, Menadione belongs to the Product Categories which include Biochemistry; Vitamins; Nutritional fortification substances; Vitamins and derivatives; Vitamin. 

2. Properties of Menadione


Physical properties of Menadione are as below: (1)ACD/LogP: 1.988; (2)ACD/LogD (pH 5.5): 1.99; (3)ACD/LogD (pH 7.4): 1.99; (4)ACD/BCF (pH 5.5): 19.09; (5)ACD/BCF (pH 7.4): 19.09; (6)ACD/KOC (pH 5.5): 287.30; (7)ACD/KOC (pH 7.4): 287.30; (8)#H bond acceptors: 2; (9)Polar Surface Area: 34.14; (10)Index of Refraction: 1.593; (11)Molar Refractivity: 47.608 cm3; (12)Molar Volume: 140.535 cm3; (13)Polarizability: 18.873×10-24 cm3; (14)Surface Tension: 46.4420013427734 dyne/cm; (15)Density: 1.225 g/cm3; (16)Flash Point: 113.801 °C; (17)Enthalpy of Vaporization: 54.487 kJ/mol; (18)Boiling Point: 304.498 °C at 760 mmHg; (19)Vapour Pressure: 0.00100000004749745 mmHg at 25°C.
 


3. Structure Descriptors of Menadione

 


You could convert the following datas into the molecular structure:
(1). InChI: InChI=1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3 
(2). InChIKey: InChIKey=MJVAVZPDRWSRRC-UHFFFAOYSA-N 
(3). Smiles: c12c(C(C=C(C1=O)C)=O)cccc2



4. Safety Information Menadione


Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38-43
Safety Statements  26-36-37/39-24
WGK Germany  3
RTECS  QL9100000
F  8
HazardClass  IRRITANT
Hazardous Substances Data 58-27-5(Hazardous Substances Data)
(1). Irritant. For being irritating to eyes and respiratory system, Menadione may cause inflammation to the skin or other mucous membranes.
(2). Harmful. This chemical may cause damage to health.

Therefore, you should take the following measure to prevent from danger.
(1). In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
(2). Wear suitable protective clothing.
(3). Wear suitable gloves and eye/face protection.
(4). Avoid contact with skin.

Below are some specific cases and your first-aid measures:
If inhalation, you should move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
If contact by skin, you should wash off with soap and plenty of water. Consult a physician.
If contact by eyes, rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed, Do NOT induce vomiting. Never give anything by mouth to an unconscious person.



5. Application of Menadione


Menadione (CAS NO.58-27-5) is used as a source of vitamin K in the treatment of hypoprothrombinemia against vitamin K deficiency.



6. Use of Menadione


Menadione could react with formaldehyde to produce 2-chloromethyl-3-methyl-[1,4]naphthoquinone, and this reaction could happen in the following conditon: reagent of acetic acid HCl.

Use of Menadione



7. Synthesis of Menadione

 

2-Methyl-[1]naphthol could react to produce Menadione, and this reaction could happen in the following conditon: reagent of NO(SO3K)2.

Synthesis of Menadione
 


8. Toxicity of Menadione


Toxicity information of Menadione are as below:



Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
chicken LDLo intraperitoneal 100mg/kg (100mg/kg)   Proceedings of the Society for Experimental Biology and Medicine. Vol. 43, Pg. 125, 1940.
mouse LD50 intraperitoneal 50mg/kg (50mg/kg)   National Technical Information Service. Vol. AD691-490,
mouse LD50 oral 500mg/kg (500mg/kg)   Proceedings of the Society for Experimental Biology and Medicine. Vol. 43, Pg. 125, 1940.
mouse LD50 subcutaneous 138mg/kg (138mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 75, Pg. 111, 1942.
rabbit LDLo oral 230mg/kg (230mg/kg) VASCULAR: OTHER CHANGES

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