Niflumic acid 4394-00-7

Details:

Product Name: Niflumic acid
Synonyms: ACIDUM NIFLUMICUM;2-(α,α,α-trifluoro-m-toluidino)nicotinic acid;ACIDUMNIFLUMICUM(NIFLUMICACID);2-[3-(Trifluoromethyl)anilino]nicotinic acid, 2-(α,α,α-Trifluoro-m-toluidino)nicotinic acid;Niflumic acid,99%;2-[(3-Trifluoromethylphenyl)amino]nicotinic Acid Niflumic Acid;Nicotinic acid Solution, 100ppm;Niflumic acid solution,100ppm
CAS: 4394-00-7
MF: C13H9F3N2O2
MW: 282.22
EINECS: 224-516-2
Product Categories: Acids and Derivatives;Heterocycles;Active Pharmaceutical Ingredients;API intermediates;Aromatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File: 4394-00-7.mol
Niflumic acid Structure
Niflumic acid Chemical Properties
Melting point  203-204 °C
Boiling point  378.0±42.0 °C(Predicted)
density  1.3935 (estimate)
storage temp.  Store at RT
solubility  Soluble in ethanol (~50 mg/ml), acetone (50 mg/ml, Clear to Slightly Hazy, Yellow), methanol (~50 mg/ml), DMSO (56 mg/ml at 25°C), and acetonitrile (~50 mg/ml).
form  neat
pka pKa 2.26 ± 0.08;4.44± 0.03(H2O,t =25±0.1,I=0.01(NaCl))(Approximate)
Water Solubility  19mg/L(room temperature)
Sensitive  Light Sensitive
Merck  14,6531
Stability: Stable, but may discolour in light. Incompatible with strong oxidizing agents. Hygroscopic.
InChIKey JZFPYUNJRRFVQU-UHFFFAOYSA-N
NIST Chemistry Reference Niflumic acid(4394-00-7)
EPA Substance Registry System 3-Pyridinecarboxylic acid, 2-[[3-(trifluoromethyl)phenyl]amino]- (4394-00-7)
Safety Information
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  26-36-36/37/39
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  QT2999100
HazardClass  6.1
PackingGroup  Ⅲ
HS Code  29333999
Toxicity LD50 in rats (mg/kg): 370 orally; 155 i.p. (Sorenson)