51-66-1

Details:

Methacetin Basic information
Product Name: Methacetin
Synonyms: 4'-METHOXYACETANILIDE;4-METHOXYACETANILIDE;4-ACETANISIDIDE;4-ACETANISIDINE;4-ACETAMIDOANISOLE;ACETYL-P-ANISIDINE;METHACETIN;LABOTEST-BB LT00053555
CAS: 51-66-1
MF: C9H11NO2
MW: 165.19
EINECS: 200-114-2
Product Categories: Intermediates of Dyes and Pigments;Anilines, Amides & Amines;Anisoles, Alkyloxy Compounds & Phenylacetates;Aromatics;Diagnostic
Mol File: 51-66-1.mol
Methacetin Structure
Methacetin Chemical Properties
Melting point  128-130 °C(lit.)
Boiling point  293.03°C (rough estimate)
density  1.1603 (rough estimate)
refractive index  1.5839 (estimate)
form  Crystalline
pka 14.53±0.70(Predicted)
Water Solubility  0.42 g/100 mL (20 ºC)
Merck  14,51
BRN  387887
CAS DataBase Reference 51-66-1(CAS DataBase Reference)
NIST Chemistry Reference N-(4-Methoxyphenyl)acetic acid amide(51-66-1)
EPA Substance Registry System Acetamide, N-(4-methoxyphenyl)- (51-66-1)
Safety Information
Hazard Codes  Xn,Xi
Risk Statements  22-36/38
Safety Statements  36-37/39-26
WGK Germany  1
RTECS  AE8290000
TSCA  Yes
HS Code  29242990
Toxicity LD50 orl-mus: 1190 mg/kg TXAPA9 19,20,71
MSDS Information
Provider Language

Methacetin Usage And Synthesis
Chemical Properties LIGHT BEIGE CRYSTALLINE POWDER
Uses Methacetin is evaluated in a breath test to predict early liver disfunction due to valproic acid and other cause. Methacetin breath test (MBT) is a rapid, non-invasive assessment of liver function in acute severe liver disease and a potential key tool in future dignosis.
Safety Profile Moderately toxic by ingestion andother unspecified routes. When heated to decomposition itemits toxic fumes of NOx.
Methacetin Preparation Products And Raw materials
Raw materials Acetic acid-->p-Anisidine
Preparation Products Disperse Blue 79-->Azoic Diazo Component 1-->4-METHOXY-2-NITROACETANILIDE-->N-(4-METHOXY-3-NITROPHENYL)ACETAMIDE