FUMITREMORGIN C high purity FUMITREMORGIN C factory supply FUMITREMORGIN C
Product Name: | FUMITREMORGIN C |
Synonyms: | FuMitreMorgin CFuMitreMorg;(5aS,12S,14aS)-1,2,3,5a,6,11,12,14a-Octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-5H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione;12alpha-Fumitremorgin C;5H,14H-Pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione,1,2,3,5a,6,11,12,14a-octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-,(5aS,12S,14aS)- |
CAS: | 118974-02-0 |
MF: | C22H25N3O3 |
MW: | 379.457 |
EINECS: | |
Product Categories: | |
Mol File: | 118974-02-0.mol |
FUMITREMORGIN C Chemical Properties |
Melting point | 259.5-260.5℃ |
storage temp. | 2-8°C |
solubility | acetonitrile: 5 mg/mL, soluble |
form | solid |
Safety Information |
Safety Statements | 22-24/25 |
WGK Germany | 3 |
FUMITREMORGIN C Usage And Synthesis |
Usage | Fumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has determined fumitremorgin C as a potent inhibitor of the breast cancer resistance protein BCRP/ABCG2 multidrug transporter. |
Usage | Fumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has recognised fumitremorgin C as a potent and specific inhibitor of the breast cancer resistance protein (BCRP/ABCG2) multidrug transporter. It reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro. |
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