UCN-01 high purity UCN-01 factory supply UCN-01
Product Name: | UCN-01 |
Synonyms: | UCN-01;7-hydroxystaurosporine;KW-2401;(9S)-2,3,10,11,12,13-Hexahydro-3α-hydroxy-10α-methoxy-9-methyl-11α-methylamino-9β,13β-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one;9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lM]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-3-hydroxy-10-Methoxy-9-Methyl-11-(MethylaMino)-, (3R,9S,10R,11R,13R)-;KRX-0601;NSC 638850;UNC 01 |
CAS: | 112953-11-4 |
MF: | C28H26N4O4 |
MW: | 482.53044 |
EINECS: | |
Product Categories: | |
Mol File: | 112953-11-4.mol |
UCN-01 Chemical Properties |
storage temp. | 2-8°C |
Safety Information |
RTECS | KC6600010 |
UCN-01 Usage And Synthesis |
Usage | UCN-01 is an indolocarbazole isolated from a high staurosporine-producing Streptomyces culture. UCN-01 inhibits protein kinase C (PKC) and cyclin-dependant kinase 2 (CDK2), resulting in accumulation of cells in the G1 phase and induction of apoptosis. UCN-01 also enhances the cytotoxicity of other anti-cancer drugs, such as DNA-damaging agents and anti-metabolite drugs, through putative abrogation of G2 and/or S phase accumulation induced by the latter agents. |
CAS NO:29911-28-2
CAS NO:32435-46-4
CAS NO:9046-10-0
CAS NO:307297-39-8
CAS NO:114435-02-8
CAS NO:10497-05-9
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View