Ranitidine Hydrochloride 66357-59-3

Superiority:

Product Name: Ranitidine Hydrochloride
Synonyms: Rantidine hydrochloride USP24;Ranitidine hydrochloride CP2000,USP24;Rantidine HCL;Ranitidine HCL BP2000/USP25;RANITIDINE HCL USP (FORM 1);RANITIDINE HCL USP (FORM 2);RANITIDINE HYDROCHLORIDE HISTAMINE H2 RE CEPTOR;Ranitidinehydrochloride,99%
CAS: 66357-59-3
MF: C13H23ClN4O3S
MW: 350.86
EINECS: 266-333-0
Product Categories: Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;AntagonistsEPA;NeatsCell Signaling Enzymes;1694 Pharmaceuticals&Personal Care Products;Histaminergics;Neurotransmitters;Substrates;Xenobiotics and Drug Metabolism;SPECTAZOLE;API
Mol File: 66357-59-3.mol

Ranitidine Hydrochloride Chemical Properties
Melting point  134°C (dec.)
storage temp.  Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility  H2O: 1.8 mg/mL
form  solid
color  tan
Water Solubility  Soluble in water, 2-hydroxypropyl-beta-cyclodextrin, acetic acid, methanol, ethanol and dimethyl sulfoxide. Insoluble in chloroform.
Sensitive  Hygroscopic
Merck  14,8110
CAS DataBase Reference 66357-59-3(CAS DataBase Reference)
Safety Information
Hazard Codes  F,T
Risk Statements  20/21/22-39/23/24/25-23/24/25-11
Safety Statements  22-24/25-45-36/37-16-7
WGK Germany  2
RTECS  KM6557000
HS Code  2932190002

Background and overview Ranitidine Hydrochloride (RHCl) is a kind of histamine H2 receptor antagonist. Since its listing in 1981, ranitidine hydrochloride has been widely used in nearly one hundred countries in the world, including China. It is clinically used for the treatment of duodenal ulcer, reflux esophagitis and Zollinger-Ellison syndrome. It is also used for the prevention of gastrointestinal bleeding caused by stress ulcer and recurrent hemorrhage of peptic ulcer. In recent decade, through the combination of ranitidine and other drugs, it has found that it has high efficiency and remarkable features in the treatment of Helicobacter pylori-positive duodenal ulcer, urticaria and post-cerebral hemorrhage stress ulcer with better efficacy than other similar drugs. Owing to its rapid effect, good potency and low price, ranitidine hydrochloride plays an important role in the anti-ulcer drug market today. Therefore, strict quality control plays important roles in guiding patients with reasonable, safe medication.