2,3-Dichlorobenzoic acid 50-45-3

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Product Name: 2,3-Dichlorobenzoic acid
Synonyms: TIMTEC-BB SBB003641;2,3-DICHLOROBENZOIC ACID;2,3-DICHLOROBENZOIC ACID PESTANAL, 250 M;2,3-Dichlorobenzoicacid,98%;2,3-Dichlorobenzoic;2,3-Dichlorbenzoesure;2,3-DICHLOROBENZOIC ACID pure;Benzoic acid, 2,3-dichloro-
CAS: 50-45-3
MF: C7H4Cl2O2
MW: 191.01
EINECS: 200-039-5
Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Benzoic acid;Organic acids;Alpha sort;D;DAlphabetic;DIA - DIC;Pesticides&Metabolites;C7;Carbonyl Compounds;Carboxylic Acids;acid;intermediate
Mol File: 50-45-3.mol

2,3-Dichlorobenzoic acid Chemical Properties
Melting point  168-170 °C(lit.)
Boiling point  273.68°C (rough estimate)
density  1.4410 (rough estimate)
refractive index  1.4590 (estimate)
form  neat
Water Solubility  slightly soluble
BRN  1946217
InChIKey QAOJBHRZQQDFHA-UHFFFAOYSA-N
CAS DataBase Reference 50-45-3(CAS DataBase Reference)
EPA Substance Registry System 2,3-Dichlorobenzoic acid (50-45-3)
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-36-24/25
WGK Germany  2
RTECS  DG6475000
HazardClass  IRRITANT
HS Code  29163990

Chemical Properties white to light yellow crystal powder
Uses 2,3-Dichlorobenzoic acid is the key intermediate for antiepileptic drug Lamotrigine (L173250) and other pharmaceuticals for the treatment of central nervous system (CNS) disorders and disease.
Purification Methods Aromatic acid impurities (to <0.05%) can be removed via the (±)--methylbenzylamine salt as described for 2,4-dichlorobenzoic acid [Ley & Yates Organic Process Research & Development 12 120 2008.] Crystallise the acid from H2O, aqueous EtOH, or 30% aqueous AcOH and several times from *C6H6, then dry it in vacuo at 40o overnight.