2'-Deoxyadenosine monohydrate 16373-93-6

Superiority:

Product Name: 2'-Deoxyadenosine monohydrate
Synonyms: 2'-Deoxyadenosine monohydrate, ≥99.0%(HPLC);2'-Deoxyadenosine Monohydrate(2'-dA H O);2′-Deoxyadenosine,Adeninedeoxyriboside,9-β-D-2′-Deoxyribofuranosidoadenine;2'-Deoxyadenosine hydrate,99%;2'-Deoxyadenosine mo;2'-Deoxy-adenosine ,98%;2'-Deoxy-β-D-adenosine Monohydrate;2'-DEOXYADENOSINE:H2O
CAS: 16373-93-6
MF: C10H13N5O3
MW: 251.25
EINECS: 683-408-7
Product Categories: Bases & Related Reagents;Intermediates & Fine Chemicals;Biochemistry;Nucleotides;Pharmaceuticals;Inhibitors;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents
Mol File: 16373-93-6.mol

2'-Deoxyadenosine monohydrate Chemical Properties
Melting point  187-189 °C
refractive index  -25.5 ° (C=0.5, H2O)
storage temp.  2-8°C
solubility  H2O: soluble50mg/mL, clear, colorless
form  powder
color  White to light beige
Water Solubility  0.3 g/100 mL (20 ºC)
BRN  5191174
Stability: Stable, but air sensitive. Incompatible with strong oxidizing agents.
InChIKey WZJWHIMNXWKNTO-VWZUFWLJSA-N
CAS DataBase Reference 16373-93-6(CAS DataBase Reference)

Safety Information
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38-20/21/22
Safety Statements  24/25-37/39-36-26
RIDADR  UN2811 6.1/PG 3
WGK Germany  3
RTECS  AU7358600
F  10-23
TSCA  Yes
HS Code  29349990

2'-Deoxyadenosine monohydrate Usage And Synthesis
Chemical Properties White crystalline powder
Uses 2'-Deoxyadenosine monohydrate is used in the synthesis of 5'-modified 2'-deoxyadenosine analogues as anti-hepatitis C virus agents.
Purification Methods Purify it by recrystallisation from H2O (hydrated crystals; solubility of the monohydrate is 1.1% in H2O at 20o). It has max 258nm (pH 1), 260nm (pH 7) and 261nm (pH 13). [Ness & Fletcher J Am Chem Soc 81 4752 1959, Walker & Butler Can J Chem 34 1168 1956.] The 3',5'-O-diacetyl derivative has m 151-152o (from EtOAc/pet ether).