480-81-9 SENECIPHYLLIN

Superiority:

Product Name: SENECIPHYLLIN
Synonyms: ALPHA-LONGILOBINE;SENECIPHYLLIN;(15cis)-12-Hydroxy-13,19-didehydrosenecionan-11,16-dione;13,19-didehydro-12-hydroxysenecionan-11,16-dione;16-dione,13,19-didehydro-12-hydroxy-senecionan-1;16-dione,13,19-didehydro-12-hydroxy-senecionin-1;NSC 30622;oxy-6-methyl-5-methylene(1,6)dioxacyclodode///
CAS: 480-81-9
MF: C18H23NO5
MW: 333.38

SENECIPHYLLIN Chemical Properties
Melting point  217°C
alpha  D -128° (chloroform)
Boiling point  470.34°C (rough estimate)
density  1.2467 (rough estimate)
refractive index  1.5740 (estimate)
storage temp.  20°C
form  neat
pka 12.43±0.20(Predicted)
Stability: Stable, but reacts with oxygen in the air. Incompatible with alkali, oxidizing agents. Store under inert gas.
CAS DataBase Reference 480-81-9
EPA Substance Registry System Seneciphylline (480-81-9)
Safety Information
Hazard Codes  T
Risk Statements  23/24/25-25
Safety Statements  1-20-24/25-45
RIDADR  1544
WGK Germany  3
HazardClass  6.1(b)
PackingGroup  III

SENECIPHYLLIN Usage And Synthesis
Description
Seneciphylline, a pyrrolizidine alkaloid, one of the main components of Chinese medicine herb Tusanqi, which is a reason of the hepatic sinusoidal obstruction syndrome (HSOS). In addition, experiments on rats have shown that seneciphylline had adverse effects on the development and organic morphodifferentiation of embryos, thus the pregnant people exposed to Hebra may get potential risk on the fetus.

Chemical Properties white powder
General Description White powder.
Air & Water Reactions Reacts slowly with atmospheric oxygen. . Insoluble in water.
Reactivity Profile SENECIPHYLLIN is readily hydrolyzed with alkali; SENECIPHYLLIN reacts readily with oxidizing agents .
Fire Hazard Flash point data are not available for SENECIPHYLLIN, but SENECIPHYLLIN is probably combustible.