1-Chloroisoquinoline 19493-44-8

Superiority:

Product Name: 1-Chloroisoquinoline
Synonyms: 1-Chloroisoquinoline, 97+%;1-Chloroisoquinoline, 97+% 5GR;1-Chloroisoquinone;Isoquinoline, 1-chloro-;1-Chloroisoquinoline 95%;1-chloro-1,2-dihydroisoquinoline;1-CHLOROISOQUINOLINE;1-CHLOROISOQUINOLINE, 98.0+%(GC)
CAS: 19493-44-8
MF: C9H6ClN
MW: 163.6
EINECS: 628-561-2
Product Categories: Other Products;Building Blocks;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;Heterocyclic Series;Quinolines;Halogenated Heterocycles;Heterocyclic Building Blocks;Isoquinolines;IsoquinolinesBuilding Blocks
Mol File: 19493-44-8.mol

1-Chloroisoquinoline Chemical Properties
Melting point  31-36 °C(lit.)
Boiling point  274-275 °C768 mm Hg(lit.)
density  1.2108 (rough estimate)
refractive index  1.6342 (estimate)
Fp  >230 °F
storage temp.  0-10°C
pka 2.03±0.30(Predicted)
form  Low Melting Solid, Crystals and/or Chunks
color  White to yellow
Water Solubility  Insoluble in water.
BRN  2996
InChIKey MSQCQINLJMEVNJ-UHFFFAOYSA-N
CAS DataBase Reference 19493-44-8(CAS DataBase Reference)
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  29334900

1-Chloroisoquinoline Usage And Synthesis
Chemical Properties white to yellow low melting solid, crystals and/or
Uses Used in a Mn-catalyzed cross-coupling with aryl- and alkylmagnesium halides.1 Also used in a Pd-catalyzed cross-coupling with heteroaryl boronic acids and esters.2
Uses 1-Chloroisoquinone is used in the preparation of new aminoisoquinolinylurea derivatives which show antiproliferative activity against melanoma cell lines. It can also be applied to the control of stor age and stability of unstable boronic acids.