490-46-0 L-Epicatechin

Superiority:

Product Name: L-Epicatechin
Synonyms: EC, L-Epicatechin;L-Epicatechin 2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol;Table son tea;(-)-Epicatechin, >=98%;(-)-Epicatechin, 98%, from green tea;5,7-trihydroxychromene;(-)-EC;(+)-EC
CAS: 490-46-0
MF: C15H14O6
MW: 290.27
EINECS: 207-710-1
Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;chiral;Aromatics;Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical Raw Materials
Mol File: 490-46-0.mol

L-Epicatechin Chemical Properties
Melting point  240 °C (dec.)(lit.)
alpha  -55～-65゜(D/20℃)(c=1,CH3OH)
Boiling point  629.2 °C
density  1.593±0.06 g/cm3(Predicted)
storage temp.  2-8°C
pka 9.54±0.10(Predicted)
form  neat
Water Solubility  Soluble in water or alcohol
Merck  13,1912
BRN  92760
InChIKey PFTAWBLQPZVEMU-UKRRQHHQSA-N
CAS DataBase Reference 490-46-0(CAS DataBase Reference)
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  KB3745000
F  10-23
HS Code  29329990
MSDS Information

L-Epicatechin Usage And Synthesis
Chemical Properties white to light yellow crystal powde
Uses Potent antioxidant and antineoplastic agent.
Uses Catechin is a polyphenolic flavonoid that has been isolated from a variety of natural sources including tea leaves, grape seeds, and the wood and bark of trees such as acacia and mahogany. Catechin is a more potent antioxidant than ascorbate or α-tocopherol in certain in vitro lipid peroxidation assays. ( )-Epicatechin is a 2R,3R stereoisomer of catechin. Like catechin, ( )-epicatechin is a powerful antioxidant. It inhibits cyclooxygenase 1 (IC50 = 3.2 μM). Also, at 100 μM, ( )-epicatechin induces apoptosis in human adenocarcinoma PC-9 cells and stimulates the inhibition of tumor necrosis factor-α release from BALB-c/3T3 cells treated with epigallocatechin gallate.
Definition ChEBI: A catechin with (2R,3R)-configuration.