3-ETHYL-3-METHYLGLUTARIMIDE 64-65-3

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Product Name: 3-ETHYL-3-METHYLGLUTARIMIDE
Synonyms: 2,6-Piperidinedione, 4-ethyl-4-methyl-;3,3-Methylethylilotarimide;2,6-DIOXO-4-METHYL-4-ETHYLPIPERIDINE;NP-13;BEMEGRIDE, 99+%;4-Ethyl-4-methylpiperidine -2,6-dione;β,β-Methylethylglutarimide;3-ethyl-3-methyl-glutarimid
CAS: 64-65-3
MF: C8H13NO2
MW: 155.19
EINECS: 200-588-0
Product Categories:
Mol File: 64-65-3.mol

3-ETHYL-3-METHYLGLUTARIMIDE Chemical Properties
Melting point  126-127 °C(lit.)
Boiling point  279°C (rough estimate)
density  1.1174 (rough estimate)
refractive index  1.4860 (estimate)
storage temp.  −20°C
pka pKa 11.7 (Uncertain)
form  powder
color  white
Merck  14,1027
CAS DataBase Reference 64-65-3(CAS DataBase Reference)
EPA Substance Registry System Bemegride (64-65-3)
Safety Information
Hazard Codes  T
Risk Statements  23/24/25
Safety Statements  22-36/37/39-45
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  MA4550000
HazardClass  6.1(a)
PackingGroup  II
Toxicity LD50 in male mice (mg/kg): 20.1 ±1.41 i.v., 43.0 ±1.8 s.c.; LD50 in male rats (mg/kg): 16.3 ±1.24 i.v., 23.5 ±1.67 i.p (Hahn, Oberdorf)

3-ETHYL-3-METHYLGLUTARIMIDE Usage And Synthesis
Chemical Properties white to off-white flakes or powder
Uses CNS stimulant;GABA antagonist
Brand name Megimide (Abbott).
General Description White crystalline solid. Sublimes at 212°F and 200 mm pressure.
Air & Water Reactions Insoluble in water.
Reactivity Profile 3-ETHYL-3-METHYLGLUTARIMIDE is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Health Hazard ACUTE/CHRONIC HAZARDS: When heated to decomposition it emits toxic fumes.
Fire Hazard Flash point data for 3-ETHYL-3-METHYLGLUTARIMIDE are not available. 3-ETHYL-3-METHYLGLUTARIMIDE is probably not flammable.
Safety Profile Poison by ingestion, intravenous, intraperitoneal, intramuscular, subcutaneous, and parented routes. Human systemic effects by ingestion: wakefulness, hallucinations, distorted perceptions, toxic psychosis. An analeptic, central nervous system stimulant; used to counteract barbiturate poisoning. When heated to decomposition it emits toxic fumes of NOx.