1-Methyl-1-nitrosourea 684-93-5

Superiority:

Product Name: 1-Methyl-1-nitrosourea
Synonyms: Nitrosomethylurea;n-methyl-n-nitroso-carbamid;N-Methyl-N-nitroso-harnstoff;n-methyl-n-nitroso-ure;NMH;NMU;N-Nitroso-N-methylcarbamide;N-Nitroso-N-methyl-harnstoff
CAS: 684-93-5
MF: C2H5N3O2
MW: 103.08
EINECS: 211-678-4
Product Categories: pharmacetical;All Aliphatics;Aliphatics;Amines
Mol File: 684-93-5.mol

1-Methyl-1-nitrosourea Chemical Properties
Melting point  119-124°C
Boiling point  193.27°C (rough estimate)
density  1.5048 (rough estimate)
refractive index  1.4264 (estimate)
storage temp.  2-8°C
pka 12.36±0.50(Predicted)
Water Solubility  14.56g/L(temperature not stated)
Stability: Stable. Flammable. Incompatible with strong oxidizing agents, strong bases, strong acids.
CAS DataBase Reference 684-93-5(CAS DataBase Reference)
NIST Chemistry Reference Urea, 1-methyl-1-nitroso-(684-93-5)
EPA Substance Registry System N-Nitroso-N-methylurea (684-93-5)
Safety Information
Hazard Codes  F,T
Risk Statements  45-46-61-11-25
Safety Statements  53-45-24/25-22
RIDADR  UN 1325 4.1/PG 2
WGK Germany  -
RTECS  YT7875000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29241990
Hazardous Substances Data 684-93-5(Hazardous Substances Data)
Toxicity LD50 oral in rat: 110mg/kg

1-Methyl-1-nitrosourea Usage And Synthesis
Chemical Properties Off-White to Pale Yellow Solid
Uses Precursor of Diazomethane. It has a cytotoxicity effect. This product contains an undetermined amount of water
General Description Pale yellow crystals or light yellow moist powder.
Air & Water Reactions Sensitive to humidity and light when pure. Insoluble in water. Slowly decomposes in water. Alkaline hydrolysis produces a highly toxic, irritating and explosive gas.
Reactivity Profile 1-Methyl-1-nitrosourea is incompatible with strong acids and bases. Also incompatible with water and nucleophilic reagents. Alkaline hydrolysis produces a highly toxic, irritating and explosive gas. Can detonate with (potassium hydroxide + methylene chloride) .
Fire Hazard Flash point data for 1-Methyl-1-nitrosourea are not available; however, 1-Methyl-1-nitrosourea is probably combustible.
Safety Profile Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by ingestion and intravenous routes. Experimental reproductive effects. Human mutation data reported. Explodes at room temperature. Can detonate with (KOH + CHzCh). When heated to decomposition it emits toxic fumes of NOx.
Carcinogenicity N-Nitroso-N-methylurea is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.