118-61-6 Ethyl 2-hydroxybenzoate

Superiority:

Product Name: Ethyl 2-hydroxybenzoate
Synonyms: RARECHEM AL BI 0029;SALICYLIC ACID ETHYL ESTER;2-hydroxy-benzoicaciethylester;Benzoicacid,2-hydroxy-,ethylester;Ethyl salicyclate;ethylhydroxylbenzoate;Mesotol;o-(Ethoxycarbonyl)phenol
CAS: 118-61-6
MF: C9H10O3
MW: 166.17
EINECS: 204-265-5
Product Categories: Aromatic Esters;Heterocyclic Compounds;Pharmaceutical Intermediates
Mol File: 118-61-6.mol

Ethyl 2-hydroxybenzoate Chemical Properties
Melting point  1 °C(lit.)
Boiling point  234 °C(lit.)
density  1.131 g/mL at 25 °C(lit.)
vapor pressure  0.05 mm Hg ( 25 °C)
FEMA  2458 | ETHYL SALICYLATE
refractive index  n20/D 1.522(lit.)
Fp  225 °F
storage temp.  Store below +30°C.
solubility  0.25g/l
pka 9.93±0.10(Predicted)
form  Liquid
color  Clear colorless to pale yellow
explosive limit 1.1%(V)
Water Solubility  slightly soluble
JECFA Number 900
Merck  14,3850
BRN  907659
InChIKey GYCKQBWUSACYIF-UHFFFAOYSA-N
CAS DataBase Reference 118-61-6(CAS DataBase Reference)
NIST Chemistry Reference Benzoic acid, 2-hydroxy-, ethyl ester(118-61-6)
EPA Substance Registry System Ethyl salicylate (118-61-6)
Safety Information
Hazard Codes  Xn,Xi
Risk Statements  22-36/38-52/53
Safety Statements  26-36
WGK Germany  1
RTECS  VO3000000
TSCA  Yes
HS Code  29182390
Toxicity LD50 orally in Rabbit: 1320 mg/kg LD50 dermal Rabbit > 5000 mg/kg

Ethyl 2-hydroxybenzoate Usage And Synthesis
Description Ethyl 2-hydroxdybenzoate is also known as Ethyl salicylate, which a kind of ester formed through the condensation between salicylic acid and ethanol. It can be used as a perfumery, artificial essence flavoring agent and used in cosmetics. It can also be used as analgesics, anti-inflammatory and antipyretic agents.
Chemical Properties clear colourless to pale yellow liquid
Chemical Properties Ethyl salicylate is the ester formed by the condensation of salicylic acid and ethanol. It is a clear liquid that is sparingly soluble in water, but soluble in alcohol and ether. It has a pleasant odor resembling winter green and is used in perfumery and artificial flavors.
Chemical Properties Ethyl salicylate has a characteristic aromatic odor similar to wintergreen. It tends to darken on exposure to light and air.
Occurrence Reported found in raspberry, tomato, currants, rum, whiskey, red wine, plum brandy, Cape gooseberry, Feijoa fruit, papaya and scotch.
Uses manufacture of artificial perfumes.
Production Methods Ethyl salicylate is found naturally in currants and strawberries . It is manufactured commercially by the esterification of salicylic acid with ethyl alcohol.
Preparation By esterification of salicylic acid with ethyl alcohol and concentrated H2SO4 at 100°C in the presence of aluminum sulfate; by heating to the boil an alkaline solution of salicylic acid and ethyl p-toluenesulfonate.
Taste threshold values Taste characteristics at 10 ppm: sweet, wintergreen, spicy and anisic.