640-68-6 D-Valine

Superiority:

Product Name: D-Valine
Synonyms: Valine, D-;ALPHA-AMINO-ISOVALERIANIC ACID;H-D-VAL-OH;D-VAL;D-VALINE;D-2-AMINOISOVALERIC ACID;(R)-α-Aminoisovaleric acid, D-2-Amino-3-methylbutanoic acid;D-Valine，α-amino isovaleric acid
CAS: 640-68-6
MF: C5H11NO2
MW: 117.15
EINECS: 211-368-9
Product Categories: Amino Acids & Derivatives;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;amino acid;Amino Acids Derivatives;Amino ACIDS SERIES;Valine [Val, V];Amino Acids and Derivatives;alpha-Amino Acids;Amino Acids;Biochemistry;Amino Acids and Derivatives
Mol File: 640-68-6.mol

D-Valine Chemical Properties
Melting point  >295 °C (subl.)(lit.)
alpha  -27.5 º (c=5, 5N HCl)
Boiling point  213.6±23.0 °C(Predicted)
density  1.2000 (estimate)
refractive index  -27 ° (C=8, 6mol/L HCl)
storage temp.  Store at RT.
solubility  56 g/L (20°C)
form  Crystalline Powder
pka 2.37±0.10(Predicted)
color  White to off-white
optical activity [α]23/D 32.0 to 24.0°, c = 8 in 6 M HCl
Water Solubility  56 g/L (20 ºC)
BRN  1721135
InChIKey KZSNJWFQEVHDMF-SCSAIBSYSA-N
CAS DataBase Reference 640-68-6(CAS DataBase Reference)
NIST Chemistry Reference 2-Amino-3-methylbutanoic acid(D)(640-68-6)
EPA Substance Registry System D-Valine (640-68-6)
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-36-26
WGK Germany  3
RTECS  YV9360000
TSCA  Yes
HS Code  29224995

D-Valine Usage And Synthesis
Description D-valine is the D-form of valine, being the non-proteinogenic isomer of valine. It can be supplemented into the cell culture for selectively inhibition of cell proliferation through inhibiting cells that are deficient in the enzyme D-amino acid oxidase. It has also been used to inhibit fibroblast growth while allowing the selective growth of epithelial cells.
Valine Valine is one kinds of the essential amino acids for human being with the requirement of adult males being 10mg/(kg d) (FAO/WHO1973). Being lack of this product can cause neurological disorders, reduction of developmental ability as well as anemia.
Valine is one of the 20 amino acids that form protein with its chemical name being 2-amino-3-methyl-butyric acid. It belongs to branched chain amino acids and is one of the eight kinds of essential amino acids and carbohydrate-producing amino acids of human body. It works together with the other two high-concentration amino acids (leucine and isoleucine) to promote the normal growth of body, tissue repair, regulate blood sugar, and provide the energy needed. When participating in intense physical activity, valine can provide extra energy to the muscles for producing glucose in order to prevent of muscle weakness. It also helps remove excess nitrogen (potentially toxic) from the liver, and transport nitrogen to all of the rest parts of the body.