Newblue-CHEM_Uridin...

Newblue-CHEM_Uridine,4-thio- 13957-31-8

Newblue-CHEM_Uridine,4-thio- 13957-31-8

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Uridine,4-thio- 13957-31-8 Uridine,4-thio-

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Details:

Product Name: 4-THIOURIDINE
Synonyms: 1-((2R,3R,4S,5R);-4-thioxo-3,4-dihydropyrimidin-2(1H);THIOURIDINE, 4-;4-THIOURIDINE;thiouridine;4-thiouridineapprox.;4-Thio-D-uridine;4-SH-Ur
CAS: 13957-31-8
MF: C9H12N2O5S
MW: 260.27
EINECS: 237-735-3
Product Categories: Biochemicals and Reagents;Nucleoside Analogs;Nucleosides, Nucleotides, Oligonucleotides;Bases & Related Reagents;Nucleotides;Sulfur & Selenium Compounds
Mol File: 13957-31-8.mol
4-THIOURIDINE Structure
4-THIOURIDINE Chemical Properties
Melting point 139-140℃ (ethanol )
storage temp. −20°C
form crystalline
color light yellow
Water Solubility Soluble in water (20 mg/ml), and methanol (10 mg/ml).
InChIKey ZLOIGESWDJYCTF-XVFCMESISA-N
CAS DataBase Reference 13957-31-8(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
MSDS Information
Provider Language
SigmaAldrich English
4-THIOURIDINE Usage And Synthesis
Uses Nucleotide analogue, essential for cell growth in certain bacterial species. This compound is also able to chelate with certain metal ions, and in tRNA it can act as a built-in antiphotomutagenic agent that protects Escherichia coli cells against mutagenesis.
Uses 4-Thiouridine is a photoreactive (crosslinking) uridine analogue that upon phosphorylation to 4-thioUTP may be incorporated into RNA structures. 4-Thiouridine may be used to study the specificity and kinetics of uridine-cytidine kinases.
Definition ChEBI: A thiouridine in which the oxygen replaced by sulfur is that at C-4.

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