High purity Thalidomide with best price and good quality

Product Name:

Thalidomide

Synonyms:

(+/-)-2-(2,6-DIOXO-3-PIPERIDINYL)-1H-ISOINDOLE-1,3(2H)-DIONE;2-(2,6-DIOXO-3-PIPERIDINYL)-1H-ISO-INDOLE-1,3(2H)-DIONE;ALPHA-PHTHALIMIDOGLUTARIMIDE;3-PHTHALIMIDOGLUTARIMIDE;(+/-)-THALIDOMIDE;THALIDOMIDE;(+/-)-N-(2,6-DIOXO-3-PIPERIDINYL)PHTHALIMIDE;N-(2,6-DIOXO-3-PIPERIDINYL)PHTHALIMIDE

CAS:

50-35-1

MF:

C13H10N2O4

MW:

258.23

Product Categories:

Intermediates & Fine Chemicals;Pharmaceuticals;API's;Cytokine signaling;Signalling;Influenza Viruses;Angiogenesis and Metastasis;Inhibitor;ROCCAL

Mol File:

50-35-1.mol

Chemical Properties

melting point 

269-271°C

boiling point 

509.7 °C at 760 mmHg

density 

1.503 g/cm3

flashing point 

262.1 °C

vapor pressure 

1.65E-10 mmHg at 25°C

storage temp. 

Store at RT

solubility 

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.6 mg/mL

Water Solubility 

<0.1 g/100 mL at 22 ºC

Stability

Stable. Combustible. Incompatible with strong oxidizing agents.

Quality Index

water：

≤0.5%

Microbial limits：

Meets the requirements

Heavey metals：

20ppm

Single impurity：

≤0.1%

Total impurities：

≤0.3%

Content：

98-101.5%

conclusion：

USP31

Usage And Synthesis

Chemical Properties

White Powder

Usage

antiinfective (topical)

Inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative. There is now a growing clinical interest in Thalidomide, and it is introduced as an immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma.

Air & Water Reactions

Insoluble in water.

Fire Hazard

Flash point data for Thalidomide are not available; however, Thalidomide is probably combustible.

Biological Activity

Teratogen, sedative-hypnotic with inherent anti-inflammatory properties. A selective inhibitor of tumor necrosis factor α (TNF- α ) synthesis.