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1 Gram	FOB Price:USD 1.0000 -5.0000

1 Gram

FOB Price:USD 1.0000 -5.0000

Min.Order :1 Gram
Purity: >98%
Payment Terms : L/C,D/A,D/P,T/T,,MoneyGram,Other

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Quick Details

Appearance:white crystal powder
Application:The circulatory system of drug ；Anti-arrhythmic drugs of Ⅲ type；Used for atrial fibrillation and atrial flutter
PackAge:Aluminum foil bag inside ,cardboard drum outside
ProductionCapacity:4|Kilogram|Week
Storage:Room temperature storage
Transportation:Mfg. add: No.9 Hexie Road, Biopark, Kaifaqu, Taihe, 236600, Anhui, China Office add: 211#Zhengfeng Building, Huanbaokejiyuan, Gaoxinqu, Jinan Contact :(86)531-82375880 Fax :(86)531-82375893 E-mail

Superiority:

The basic information

More than a little (115256-11-6) is one of the more specific the first Ⅲ anti-arrhythmic drugs, it is to extend the time of action potential and effective refractory period, but does not affect the heart conduction velocity. The mechanism of these effects is that it can inhibit the fast part of the hysteresis outward potassium current, thus blocking the outflow of potassium ions during the repolarization phase. Relevant research shows that the drug can treat and prevent atrial arrhythmia, such as atrial fibrillation, atrial flutter and paroxysmal supraventricular tachycardia, but also prevent the occurrence of ventricular tachycardia. It has been shown to reduce the incidence of complications in patients with heart failure. The most serious adverse reaction to Dofeirite is the induction of ventricular arrhythmias (especially tip torsive ventricular tachycardia).

Details:

Advantage

The mechanism of action is to block the fast part of the potassium channel in the heart, and prolong the action potential duration (Ikr). In several important concentrations, polyphilite only blocks Ikr, and has no correlation with other potassium ion current repolarization (e.g., Iks,Ik1). In clinically relevant concentrations, a little more on the sodium channel (associated with drug Ⅰ class), adrenergic receptor alpha or adrenergic receptor beta.

[Purpose 1]

Selective potassium channels agonists for Ⅲ anti-arrhythmic drugs, used for atrial fibrillation and atrial flutter.

[Purpose 2]

For maintenance and conversion to normal sinus rhythm in patients with atrial fibrillation (AF) and atrial flutter (AFL).

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