Supply Mirabegron with low price for sale

Min.Order / FOB Price:Get Latest Price

1 Gram	Negotiable

1 Gram

Negotiable

Min.Order :1 Gram
Purity: 99%
Payment Terms : L/C,T/T,Other

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Mirabegron for sale Supply Mirabegron Mirabegron with low price

Quick Details

Appearance:White to off-white powder
Application:Pharmaceutical products
PackAge:1KG; 10KG; 25KG
ProductionCapacity:200|Kilogram|Month
Storage:
Transportation:by air, by courier or by sea

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Supply Mirabegron with low price for sale

Mirabillon relaxes and increases the stability of the detrusor by acting on the 3 receptor. Three receptor subtypes (1, B2, and 3) were found in human detrusor cells and epithelial cells of the urethra. MRNAChemicalbook of the 3 receptor was mainly expressed in human detrusor smooth muscle cells, accounting for 97% of the receptor mRNA in bladder tissues. The expression of receptor mRNA and the function of its signaling pathway suggest that 3 receptor plays a pivotal role in normal and diseased bladders.

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Mirabelone is a line drug in the treatment of bladder hyperactivity with obvious curative effect, clear mechanism of action and little side effect.

And now its API synthesis yield is very low, cost, product impurities, purification is difficult, so the synthesis of mira veron and each steps of process optimization research is particularly important, p-nitrophenyl) and (R) - styrene oxide as raw materials via ring-opening reaction, reduction reaction and condensation, the product get mira veron.

The synthesis process was improved and optimized, and the optimum conditions for each step were determined by several experiments, the optimum molar ratio was 1:1.2, the solvent to raw material mass ratio was 10:1, the reaction time was 5h, and mirabillon and its key intermediates were confirmed by analysis and test. The reaction route has the advantages of low production cost, mild reaction, simple operation and high total yield. The rice was synthesized by analysis

The main impurity of Labelon is the removal of hydroxyl mirabelon.

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