- Min.Order :1 Kilogram
- Purity: 98.5%
- Payment Terms : L/C,D/A,T/T,
Keywords
33419-42-0 Etoposide 4-demethylepipodophyllotoxin-beta-d-ethylideneglucoside
Quick Details
- Appearance:Almost white to white crystalline powder
- Application:Metabolism Drug; Carcino-Chemotherapeutic Drug;Antineoplastic
- PackAge:25kg/drum
- ProductionCapacity:700|Kilogram|Day
- Storage:Protect from humidity; keep in a dry, cool, and shady place.
- Transportation:by sea,air
Superiority:
1. Superior quality
2.Competitive price
3. Good service
4 Flexible payment
Etoposide
CAS: 33419-42-0
Appearance:Almost white to white crystalline powder
Assay: NLT 99.0%
Packing: 1kg/aluminum tin; 25kg/carton barrel.
Storage: Protect from humidity; keep in a dry, cool, and shady place.
Details:
Specification of Etoposide
| Items | Specifications | Results |
| Appearance | White to off-white fine crystalline powder. | Conforms |
| Solubility | Very slightly soluble in water; slightly soluble in alcohol, in chloroform, in ethyl acetate, and in methylene chloride; sparingly soluble in methanol. | Conforms |
| Identification | A. IR spectrum exhibits maxima only at the same wavelengths as that of the reference standard. | Confomrs |
| B. The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay. | Conforms | |
| Specific Optical Rotation | Between -110° and -118° | -114° |
| Water | Not more than 6.0% | 0.41% |
| Residue on Ignition | Not more than 0.1% | 0.02% |
| Heavy metals | Not more than 0.002% | <0.002% |
| Related substances (HPLC) | Lignan P: Not more than 0.5% | <0.05% |
| Picroetoposide: Not more than 1.0%. | <0.0021% | |
| Total related compounds: Not more than 2.0% | 1.40% | |
| Residual Solvent | Ethanol: Not more than 5000ppm | 24ppm |
| Chloroform: Not more than 60ppm | Not detected | |
| Assay(HPLC) | 95.0% to 105.0% of C29H32O13 on the anhydrous basis. | 98.50% |
| Packaging and Storage | Preserve in tight, light-resistant containers. | |
| Conclusion: The test results indicate the product complies with the specifications | ||
Usage of Etoposide
1) Etoposide is used as a form of chemotherapy for cancers such as Kaposi’s sarcoma, Ewing's sarcoma,
lung cancer, testicular cancer, lymphoma, nonlymphocytic leukemia, and glioblastoma multiforme.
2) It is often given in combination with other drugs (such as bleomycin in treating testicular cancer).
3) It is also sometimes used in a conditioning regimen prior to a bone marrow or blood stem cell transplant
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