Mesna 19767-45-4

Min.Order / FOB Price:Get Latest Price

1 Kilogram	FOB Price: USD 1.0000

1 Kilogram

FOB Price: USD 1.0000

Min.Order :1 Kilogram
Purity: 99%min
Payment Terms : L/C,D/A,D/P,T/T,

Keywords

19767-45-4 sodium 2-mercaptoethanesulfonate Mesna

Quick Details

Appearance:White to off-white powder
Application:pharmaceutical, Oncology drug
PackAge:25kg/drum
ProductionCapacity:1500|Metric Ton|Year
Storage:Protect from humidity; keep in a dry, cool, and shady place.
Transportation:by sea,air

Superiority:

Mesna is an organosulfur compound. It is used in cancer chemotherapy involving cyclophosphamide and ifosfamide as an adjuvant. It is an acronym for 2-Mercaptoethane sulfonate Na (Na being the symbol for sodium). Mesna is used therapeutically to reduce the incidence of haemorrhagic cystitis and haematuria when a patient receives ifosfamide or cyclophosphamide for cancer chemotherapy. These two anticancer agents, in vivo, may be converted to urotoxic metabolites such as acrolein. It assists to detoxify these metabolites by reaction of its sulfhydryl group with the vinyl group. It also increases urinary excretion of cysteine

Details:

Item	Specification
Specific rotation	+39.5 to +41.5°
State of solution(transmittance)	Clear 98.0% min.
Chloride[cl]	0.020% max.
Ammonium [NH4]	0.02% max.
Sulfate[SO4]	0.020% max
Iron[Fe]	10ppm max.
Heavy metals [Pb]	10ppm max
Arsenic[As2O3]	1ppm max
Other amino acids	Chromatographically not detectable
Loss on drying	0.20% max.
Residue on ignition[sulfated]	0.10% max.
Assay	99.0% min