Decitabine 2353-33-5

Min.Order / FOB Price:Get Latest Price

1 Kilogram	FOB Price: USD 1.0000

1 Kilogram

FOB Price: USD 1.0000

Min.Order :1 Kilogram
Purity: 99.5%min
Payment Terms : L/C,D/A,D/P,T/T

Keywords

5-azadeoxycytidine Decitabine 5-Aza-2'-deoxycytidine

Quick Details

Appearance:white or almost white crystalline powder
Application:pharmaceutical
PackAge:25kg/drum
ProductionCapacity:2000|Metric Ton|Year
Storage:Protect from humidity; keep in a dry, cool, and shady place.
Transportation:by sea,air

Superiority:

Cyproterone acetate has antagonistic properties towards the 5-Aza-2'-Deoxycytidine, has been reported to cause phosphorylation inhibition of 2'-deoxycytidine in certain cells and the incorporation of 2'-deoxycytidine into DNA. Experiments have shown that this compound induces changes in the differentiated state of cultured mouse embryo cells and additionally inhibits Dnmt (DNA methyltransferase). DNA methylation has been noted to be important in determining apoptotic susceptibility to histone deacetylase inhibitors, and its prevention can cause gene silencing and transcriptional repression. Other studies suggest that cell exposure to 5-Aza-2'-Deoxycytidine causes a change in replication timing, reactivation of repressed genes, and decondensation of heterochromatin. Furthermore, this agent demonstrates the ability to induce histone hyperacetylation in murine centromeric heterochromatin and also affect intranuclear distribution of histone deacetylase 2.

Details:

Decitabine 99.5%

CAS No.136572-09-3
largest unknown impurities NMT 0.1%
Total impurities NMT 1.0%
Manufacturer since 2005

Decitabine 99.5%
largest unknown impurities NMT 0.1%
Total impurities NMT 1.0%

Formula: C8H12N4O4

Formula weight: 228.20

Formula structure:
Manufacture 5-azadeoxycytidine/ Decitabine /Dacogen 2353-33-5 99%min

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