Quinapril

Quinapril

Quinapril

Min.Order / FOB Price:Get Latest Price

5 Kilogram

FOB Price: USD 1.0000

  • Min.Order :5 Kilogram
  • Purity: 99%min
  • Payment Terms : L/C,T/T,

Keywords

85441-61-8 QUINAPRIL HCL ACCUPRIN

Quick Details

  • Appearance:POWDER
  • Application:Cardiovascular Drug; Antihypertensive
  • PackAge:25kg carton drum
  • ProductionCapacity:10000|Metric Ton|Year
  • Storage:Keep in cool and dry place. Keep away from heat source and direct sunlight.
  • Transportation:by sea

Superiority:

Quinapril  is an angiotensin-converting enzyme inhibitor (ACE inhibitor) used in the treatment of hypertension and congestive heart failure. A prodrug, it is converted to its active metabolitequinaprilat, in the liver.

Quinapril inhibits angiotensin converting enzyme, an enzyme which catalyses the formation of angiotensin II from its precursor,angiotensin I. Angiotensin II is a powerful vasoconstrictor and increases blood pressure through a variety of mechanisms. Due to reduced angiotensin production, plasma concentrations of aldosterone are also reduced, resulting in increased excretion of sodium in the urine and increased concentrations of potassium in the blood.

Quinapril is indicated for the treatment of high blood pressure (hypertension) and as adjunctive therapy in the management of heart failure. It may be used for the treatment of hypertension by itself or in combination with thiazide diuretics, and with diuretics and digoxin for heart failure.

PHYSICAL AND CHEMICAL PROPERTIES

Molecular Formula:

C25H30N2O5.HCl

Molecular Weight: 474.98
CAS No.: 85441-61-8
Stability:
3 years -20°C Powder
6 months -80°C in solvent
Molecular Structure:

 

 

ANALYTICAL DATA

HPLC: 99.07% purity 
NMR: Consistent with structure

Packaging & Shipping

 Packaging :- 25 kg Fiber drum or as per Customer requirement 

 

Details:

product Name Quinapril
Synonyms Accupril; Asig
Molecular Formula C25H30N2O5
Molecular Weight 438.52
InChI InChI=1/C25H30N2O5/c1-3-32-25(31)21(14-13-18-9-5-4-6-10-18)26-17(2)23(28)27-16-20-12-8-7-11-19(20)15-22(27)24(29)30/h4-12,17,21-22,26H,3,13-16H2,1-2H3,(H,29,30)/t17-,21-,22-/m0/s1
CAS Registry Number 85441-61-8
Molecular Structure 85441-61-8 Quinapril
 
Melting point 120-130℃
Hazard Symbols  
Risk Codes  
Safety Description S22:;
S24/25:;

 

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