145040-37-5 Candesartan cilexetil 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylate
Candesartan cilexetil CAS 145040-37-5
Description:
Product Name: |
Candesartan cilexetil |
Synonyms: |
1-[[(cyclohexyloxy)carbonyl]oxy]ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylate |
CAS RN.: |
145040-37-5 |
EINECS: | Add |
Molecular Weight: | 610.66 |
Molecular Formula: | C33H34N6O6 |
refractive_index: | 1.665 |
TEMS |
STANDARD |
RESULTS |
APPEARANCE |
WHITE TO OFF-WHITE POWDER |
WHITE POWDER |
SOLUBILITY |
PRACTICALLY INSOLUBLE IN WATER, FREELY SOLUBLE IN METHYLENE CHLORIDE, SLIGHTLY SOLUBLE IN ANHYDROUS ETHANOL |
COMPLIES |
IDENTIFICATION |
IR SPECTURE SHOULD BE IDENTICAL TO THAT OF CANDESRATAN CILEXETIL STANDARD
THE RETENTION TIME OF THE MAJOR PEAK OF THE SAMPLE SOLUTION CORRESPONDS TO THAT OF THE SYANDARD SOLUTION |
COMPLIES
COMPLIES |
WATER |
NMT 0.3% |
0.1% |
RESIDUE ON IGNITION |
NMT 0.1% |
<0.1% |
RELATED COMPOUNDS(HPLC) |
ETHYI CANDESARTAN NMT 0.2% DESETHYL CANDESARTAN CILEXETILNMT0.3% N2-ETHYL CANDESARTAN CILEXE: NMT0.2% ANY OTHER UNKOWN IMPURITY: NMT0.1% TOTAL IMPURITIES: NMT 0.6% |
0.05%
0.01% 0.01% 0.03% 0.12% |
ASSAY |
98.7%-101.0% ON THE ANHYDROUS BASIS |
100.5% |
RESIDUAL SOLVENTS (GC) |
ACETONE: NMT 5000PPM METHANOL:NMT3000PPM METHYLENE CHLORIDE: NMT600PPM DIETHYL ETHER: NMT5000PPM ETHYL ACETATE: NMT 5000PPM DIMETHYLFORMAMIDE:NMT 880PPM |
21PPM N.D N.D N.D N.D N.D |
PARTICLE SIZE |
FOR REFERENCE ONLY |
D50:4UM D90:13UM |
CONCLUSION |
IT CONFORMS TO USP37 |
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