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129101-54-8 Rivastigmine tartrate Rivastigmine hydrogen tartrate
Chemical Name: (S)-N-Ethyl-3-[(1-dimethylamino)ethyl]-N-methylphenylcarbamate hydrogen tartrate
Cas No.: 129101-54-8
Molecular Formula: C18H28N2O8
Molecular Weight: 400.42
InChI: 1S/C14H23N2O2.C4H6O6/c1-6-16(5,14(17)18)13-9-7-8-12(10-13)11(2)15(3)4;5-1(3(7)8)2(6)4(9)10/h7-11H,6H2,1-5H3,(H,17,18);1-2,5-6H,(H,7,8)(H,9,10)/p-1
Usage: A brain selective acetylcholinesterase inhibitor. Nootropic.
Boiling Point: 864.2 °C
Appearance: white powder
Assay:99%min
Rivastigmine is a acetylcholinesterase inhibitor used for the treatment of mild to moderate Alzheimer's diseaseand Parkinson's. The drug can be administered orally or via a transdermal patch; the latter form reduces the prevalence of side effects,[1]which typically include nausea and vomiting.
The drug is eliminated through the urine, and appears to have relatively few drug-drug interactions.
Item |
Specifications |
Results |
Appearance |
An orange,crystalline powder |
Conforms |
Solubility |
Soluble in 16 parts of water |
Conforms |
Identification |
Positive |
Conforms |
Acidity |
PH of 1%w/v solution,2.5to3.5 |
3.1 |
Loss on drying |
≤0.5 |
0.29 |
Melting point |
200-205°C |
200.1°C |
Assay |
≥98.5% |
98.56 |
Conclusion |
Complies with BP98 |
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