Aprepitant

Aprepitant

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1 Metric Ton

FOB Price:USD 1.0000 -2.0000

Min.Order :1 Metric Ton
Purity: 99%min
Payment Terms : L/C,T/T

Keywords

170729-80-3 Aprepitant 5-{[(2R,3S)-2-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)morpholin-4-yl]methyl}-1,2-dihydro-3H-1,2,4-triazol-3-one

Quick Details

Appearance:White powder
Application:Central Nervous System Drug; Anti-Emetic and Antinauseant
PackAge:drum
ProductionCapacity:1000|Metric Ton|Year
Storage:Store in cool and dry place, away from sun light.
Transportation:By sea or by air

Superiority:

Name	Aprepitant
CAS No	170729-80-3
MF	C23H21F7N4O3
Purity	99%
Appearance	white powder

Details:

Item	Specification		Test Results
Description	Off-white to light yellow powder		Conforms
Identification IR	HPLC, IR		Conform
Specific optical rotation	+68.0° ±3° (c=1.0, in Methanol)		67.49°
Melting point	248±5 °C		248 -250°C
Water	≤0.5%		0.29%
Heavy metals	≤10ppm		Conforms
Residue on ignition	Not more than 0.1%		0.07%
Related substances	Desfluoro aprepitant NMT 0.15% R,R,R-Diastereomer: NMT 0.15% Any other individual impurity: NMT 0.10% Total impurities: NMT 0.50%		0.09% 0.08% 0.06% 0.29%
Enantiomer purity	NMT 0.15% of the S,R,S-enantiomer		0.07%
Assay (HPLC)	NLT 98.0% and NMT 102.0% (on the anhydrous basis)		99.9%
Organic volatile impurities	Methanol NMT 2500 ppm; Xylene NMT 2170 ppm; Toluene NMT 890 ppm; DMSO NMT 5000ppm		Conforms
Conclusion: Conforms to Authorized USP Pending Monograph

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