79794-75-5 Loratadine Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate
Loratadine
Assay: 99% min
CAS:79794-75-5
Molecular formula:C22H23ClN2O2
Molecular weight: 382.89
Purity: 99%
Appearance: White crystalline powder
Loratidine; Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate; 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester.
Loratadine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Test Item |
Standard: USP |
Character |
White or off-white crystalline powder |
Melting range |
132~137 |
Identification |
IR spectrum similar to that of RS |
HPLC retention time similar to that of RS |
|
Related substance |
Total impurities: NMT0.3% |
Single impurity: NMT0.1% |
|
Heavy metals |
NMT 10ppm |
Loss on drying |
NMT0.5% |
Residue on ignition |
NMT0.1% |
Assay |
98.5%-101.0% |
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