162401-32-3 Roflumilast 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide
Product name | Roflumilast |
Synonyms |
3-CyclopropylMethoxy-N-(3,5-dichloro-pyridin-4-yl)-4-isopropoxy-benzaMide;APTA 2217;3-Cyclopropylmethoxy-4-difluoromethoxy-N-[3,5-dichloropyrid-4-yl]-benzamide;162401-32-3;Roflumilast intermediates;Roflumilast, >=99%;ROFLUMILAST;3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide
|
Cas | 162401-32-3 |
MF | C17H14Cl2F2N2O3 |
MW | 403.2074664 |
EINECS | 685-382-2 |
Product Categories | Roflumilast;Daxas;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;API;Pharmaceuticals;APIs |
Items |
Standards |
Results |
Appearance |
White to almost white powder |
Conforms |
Identification |
NMR |
Conforms |
Solubility |
Hardly soluble in water, easily soluble in acetonitrile. |
Conforms |
Melting point |
155℃~159℃ |
157.2℃~158.1℃ |
Loss on drying |
≤0.5% |
0.33% |
Single impurity |
≤0.5% |
0.24% |
Residue on ignition |
≤0.3%. |
0.22% |
Heavy metals |
≤10ppm |
Conforms |
Purity by HPLC |
≥99.0% |
99.57% |
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