90098-04-7 Rebamipide 2-(4-Chlorobenzoylamino)-3-(1,2-dihydro-2-oxo-4-quinolyl)propionic acid
Name | Rebamipide |
CAS | 90098-04-7 |
MF | C19H15ClN2O4 |
MW | 370.79 |
MP | 288-290°C dec. |
Storage temp | -20°C Freezer |
Assay | 99% Min. |
Appearance | White Powder |
Usage |
It is used for treating stomach ulcers. It is a kind of novel anti-ulcer drugs. |
Item |
Specification |
Appearance |
White crystalline powder,bitter taste |
Solubility |
Soluble in N,N dimethylformamide;very slightly soluble or practically insoluble in methanol and ethanol; practically insoluble in water. |
Optical Rotation |
No optical rotation in N,N’-dimethylformamide(1→20) |
Melting point |
About 291℃(Decomposition) |
Identification |
Conforms |
Loss on drying |
≤3.0% |
Sulphated ash |
≤0.10% |
Heavy metals |
≤10ppm |
Chlorides |
≤280ppm |
Related Substance |
M-chloro isomer≤0.15% O-chloro isomer≤0.15% Debenzoylated isomer≤0.15% Other single impurity≤0.1% Total impurities≤0.4% |
Residual solvent |
Acetone≤0.5% Ethanol≤0.5% Acetic acid≤0.5% Dichloromethane≤0.06% Methanol≤0.3% |
Assay |
99.0%~101.0%(Calculated on dry basis) |
Conclusion |
Conform to the specification of JP16 |
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