88495-63-0 Artesunate Artemisinin monosuccinat
Product name: Artesunate
Synonym: Artesunatum
CAS NO.: 88495-63-0
M.F. &M. W. : C19H28O8; 384.43
Plants source: composites Artemisia annua L. leaf.
Appearance: white crystal powder
Melting point:132℃-135℃, odorless, bitter taste
Item |
Specification |
Test Results |
Test Method |
Appearance |
White crystalline powder, odorless, almost tasteless |
Complies |
Visual |
Identification |
A ,IR B , TLC C ,Chemical reaction D ,Chemical reaction |
Positive Positive Complies Complies |
IR TLC Visual Visual |
Particle Size |
95% pass through 80 mesh |
Complies |
US Screen |
Melting point |
132 ºC ~ 135ºC |
133ºC |
Melting pointApparatus |
Optical rotation |
+2.5 ° ~ +3.5 ° |
+3.4° |
Polarimeter |
pH (1%Suspension) |
3.5 ~4.5 |
4.3 |
pH meter |
Chloride |
≤0.02% |
<0.02% |
CP2010 |
Related substances |
|||
-0.5% ≤impurities ≤1.0% |
No most than one |
One |
HPLC |
-Total impurities |
≤2.0% |
0.59% |
HPLC |
Heavy metals |
≤20ppm |
<20ppm |
Visual Colorimetry |
Sulphated Ash |
≤0.1% |
0.05% |
CP2010 |
Loss on drying |
≤0.5% |
0.15% |
CP2010 |
Assay by HPLC |
98.0% ~102.0% |
99.21% |
HPLC |
Conclusion:The above materials conform with IP |
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