55-48-1 Atropine Sulphate Atropine sulfate anhydrous
Atropine Sulfate
Atropine produces many effects in the body, including relief from spasms of the gastrointestinal tract (stomach and intestines), the bladder, and the biliary tract. This is helpful in controlling conditions such as colitis, spastic bladder, diverticulitis, infant colic, renal and biliary colic, peptic ulcer, and irritable bowel syndrome.
Atropine also reduces the secretions of many organs, thereby helping to control conditions such as excessive stomach acid production and excessive secretion from the pancreas; to reduce secretions of the nose, lungs, salivary glands, and stomach before surgery; and to help dry up excessive mucus production associated with diseases, infections, and allergies.
Atropine is used to treat the rigidity, tremor, excessive salivation, and sweating caused by Parkinson's disease.
ITEMS |
SPECIFICATION-USP34 |
|
APPEARANCE |
WHITE OR ALMOST WHITE CRYSTALLINE POWDER OR LOLORLESS CRYSTALS |
|
SOLUBILITY |
FREELY SOLUBLE IN WATER OF 96% ETJAMP; [RACTOCA;;U OMSP;IB;E OM AETJER |
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IDENTIFICATION |
||
OPTICAL ROTATION |
-0.50 . - +0.50. |
|
INFRARED ABSORPTION |
CONFORMS WITH THE SPECTRUM OF RS |
|
CHEMICAL REACTION |
MEETS THE REQUIREMENTS |
|
CHEMICAL REACTION |
SHOULD BE POSITIVE |
|
THE REACTION OF SULPHATES |
SHOULD BE POSITIVE |
|
THE REACTION OF ALKALOIDS |
SHOULD BE POSITIVE |
|
PH(ACIDITY) |
4.5-6.2 |
|
OPTICAL ROTATION |
-0.50. - + 0.05. |
|
COMPOUNDS |
IMPURITIES A≤0.2% |
|
|
IMPURITIES B≤0.2% |
|
|
IMPURITIES C≤0.2% |
|
|
IMPURITIES D≤0.2% |
|
|
IMPURITIES E≤0.3% |
|
|
IMPURITIES F≤0.2% |
|
|
IMPURITIES G≤0.2% |
|
|
IMPURITIES H≤0.3% |
|
|
UNSPECIFIED IMPURITIES≤0.10% |
|
|
TOTAL ≤0.5% |
|
WATER CONTENT |
2.0-4.0% |
|
SULPHATED ASH |
NOT MORE THAN 0.1% |
|
ASSAY |
98.5%-101.0% CALCULATED ON THE DRIED BASIS |
|
RESIDUAL SOLVENT IMPURITIES ACETONE |
NOT MORE THAN 0.25% |
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