179463-17-3 Cancidas Caspofungin acetate
Name:Caspofungin acetate
CAS:179463-17-3
Appearance:White powder
Application: Pharmaceutical Raw Intermediates
Item |
Specifications |
Result |
Appearance |
White or almost white powder |
Off white powder |
Indentification |
HPLC:The retention time of principle peak obtained from Test solution should conform with that obtained from Standard solution, as test in Assay |
Conforms |
IR: Spectrum of Test sample should conform to that of Caspofungin Acetate Reference Standard |
Conforms |
|
Specific Optical Rotation |
-102.0°~108.0 ° |
-105.3° |
PH |
5.0~7.0 |
6.5 |
Water |
10.0% |
7.5% |
Solution color and clarity |
Solution should be clear colorless |
Conforms |
Related substances I |
Impurity A: NMT 0.10% |
ND |
Impurity B: NMT 0.10% |
ND |
|
Impurity D: NMT 0.30% |
0.17% |
|
Impurity E: NMT 0.10% |
ND |
|
Unspecified impurity F: NMT 0.10% |
0.03% |
|
Unspecified impurity G: NMT 0.10% |
ND |
|
Pneumocandin B0: NMT 0.10% |
ND |
|
Each of unspecified impurity : NMT 0.10% |
0.04% |
|
Total impurity: NMT 1.0% |
0.24% |
|
Related substances II |
Impurity C: NMT 0.10% |
0.03% |
Acetic acid |
9.0%~11.0%(calculated on anhydrous basis) |
10.1% |
Heavy Metal as Pb |
NMT 10ppm |
Conforms |
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