13311-84-7 Flutamide 2-Methyl-N-[4-nitro-3-(trifluoromethyl)-phenyl]-propionamide
Product name:Flutamide
CAS No: 13311-84-7
EINECS No.:236-341-9
Formula:C11H11F3N2O3
Appearance:Light Yellow Crystalline Powder
Purity:99%MIN
Assay:HPLC
Characteristics |
Light yellow needle crystal |
Light yellow needle crystal |
Identification |
Meets the requirements |
Meets the requirements |
Melting Point |
110-114°C( does not exceed 2°C) |
111.5-112.0°C |
Loss on Drying |
Not more than 0.5% |
0.3% |
Residue on ignition |
Not more than 0.1% |
0.08% |
Relative Substance |
4-Nitro-3-trifluoroethylacetanilide: NMT: 0.2% |
0.09% |
4-Nitro-3-trifluoromethylaniline: NMT: 0.15% |
Not detected |
|
3-trifluoromethylaniline: NMT: 0.2% |
0.02% |
|
4-Nitro-3-trifluoromethylpropionanilide: NMT: 0.3% |
Not detected |
|
3-trifluoromethylisobutyranilide: NMT: 0.2% |
Not detected |
|
o-Flutamide:NMT: 0.2% |
Not detected |
|
Unknown(relative response:1.0) : NMT: 0.05% |
Not detected |
|
Total unknown:NMT: 0.1% |
Not detected |
|
Total impurities:NMT: 0.4% |
0.11% |
|
Solubility |
Freely soluble in acetone ethyl acetate soluble in chloroform other practically insoluble mineral oil. petroleum ether and water |
Meets the requirements |
Heavy Metals |
Not more than10ppm |
Not detected |
Content |
98.0-101.0%(calculated on the dried basis) |
100.3% |
Conclusion :Complies with USP30 |
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