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Quinidine Quinidine free base 56-54-2
Quinidine 99.0% Cas 56-54-2
Basic Information:
Productname |
Quinidine |
CAS NO. | 56-54-2 |
MF | C20H25N2O2 |
Synonym | 6-Methoxy-alpha-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol; alpha-(6-Methoxy-4-quinolyl)-5-vinyl-2-quinuclidinemethanol; beta-Quinine |
Category | Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug |
Appearance | White to off-white crystalline powder |
Storage | should be stored in a well-closed container at low temperature |
Package | 1kg/bag, 25kgs/drum or at your demands |
Indication:
For the treatment of ventricular pre-excitation and cardiac dysrhythmias
Pharmacodynamics:
Quinidine, a hydantoin anticonvulsant, is used alone or with phenobarbital or other anticonvulsants to manage tonic-clonic seizures, psychomotor seizures, neuropathic pain syndromes including diabetic neuropathy, digitalis-induced cardiac arrhythmias, and cardiac arrhythmias associated with QT-interval prolongation.
Mechanism of Action:
Quinidine acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation. The antiarrhythmic actions are mediated through effects on sodium channels in Purkinje fibers. Quinidine may also act on the slow inward calcium current (ICa), the rapid (IKr) and slow (IKs) components of the delayed potassium rectifier current, the inward potassium rectifier current (IKI), the ATP-sensitive potassium channel (IKATP) and Ito.
High Quality Quinidine 56-54-2
Item |
Requirements |
Test Results |
Description |
A white or almost white crystalline powder |
white crystalline powder |
Infrared spectrum appraisal |
Complies |
Complies |
Rotation |
250~255(ethanol) |
253 |
Melting point |
169C~174C |
172C |
Loss on drying |
≤1.00% |
0.60% |
Sulfate |
≤500ppm |
Complies |
Chloride |
≤250ppm |
Complies |
Other quinine anhydrous |
≤1.50% |
0.40% |
Residue on ignition |
≤0.10% |
0.05% |
Heavy Metal |
≤10ppm |
Complies |
Assay |
≥98.0% |
99.78% |
Conclusion |
Meets the Requirements |
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