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GMP Manufacturer Quinidine 99% CAS:56-54-2

GMP Manufacturer Quinidine 99% CAS:56-54-2

Min.Order / FOB Price:Get Latest Price

1 Kilogram

FOB Price: USD 1.0000

  • Min.Order :1 Kilogram
  • Purity: 99%min
  • Payment Terms : L/C,D/A,D/P,T/T

Keywords

Quinidine Quinidine free base 56-54-2

Quick Details

  • Appearance:white or almost white crystalline powder
  • Application:Cardiovascular Drug; Antiarrhythmic, Antimalarial
  • PackAge:25Kg/Drum
  • ProductionCapacity:2000|Metric Ton|Year
  • Storage: Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
  • Transportation:by sea,air

Superiority:

Quinidine 99.0% Cas 56-54-2   

 

Basic Information: 

Productname 

Quinidine           

CAS NO. 56-54-2
MF C20H25N2O2              
Synonym 6-Methoxy-alpha-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol; alpha-(6-Methoxy-4-quinolyl)-5-vinyl-2-quinuclidinemethanol; beta-Quinine
Category Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug
Appearance White to off-white crystalline powder
Storage should be stored in a well-closed container at low temperature
Package 1kg/bag, 25kgs/drum or at your demands

 

Indication:

For the treatment of ventricular pre-excitation and cardiac dysrhythmias

Pharmacodynamics:
Quinidine, a hydantoin anticonvulsant, is used alone or with phenobarbital or other anticonvulsants to manage tonic-clonic seizures, psychomotor seizures, neuropathic pain syndromes including diabetic neuropathy, digitalis-induced cardiac arrhythmias, and cardiac arrhythmias associated with QT-interval prolongation.

Mechanism of Action:

Quinidine acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation. The antiarrhythmic actions are mediated through effects on sodium channels in Purkinje fibers. Quinidine may also act on the slow inward calcium current (ICa), the rapid (IKr) and slow (IKs) components of the delayed potassium rectifier current, the inward potassium rectifier current (IKI), the ATP-sensitive potassium channel (IKATP) and Ito.

packing

Quinine Base powder cas 56-54-2

 

Details:

High Quality Quinidine 56-54-2

 

 

Item

Requirements

Test Results

Description

A white   or almost white crystalline powder

white crystalline powder

Infrared spectrum appraisal

Complies

Complies

Rotation

250~255(ethanol)

253

Melting point

169C~174C

172C

Loss on drying

1.00%

0.60%

Sulfate

500ppm

Complies

Chloride

250ppm

Complies

Other quinine anhydrous

1.50%

0.40%

Residue on ignition

0.10%

0.05%

Heavy   Metal

≤10ppm

Complies

Assay

≥98.0%

99.78%

Conclusion

Meets the Requirements

 

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