manufacturer supplier Reserpine 99% CAS 50-55-5

Details:

2. Introduction:  

Rauwolfia extract / Extractum Radix Rauvolfia /  RAUWOLFIA SERPENTINA EXTRACT / Rauwolfia serpentina P.E 98% 99%

Reserpine is extracted from the root of Rauwolfia vomitoria, plants found extensively in Africa. 

Rauwolfia extract is an alkaloid derived from Rauwolfia Vomitoria Root Bark.

Rauwolfia extract is a naturally occurring drug that has been used for centuries in ancient India.

In traditional herbal medicine, rauwolfia extract was brewed as a tea and used in humans to treat hypertension, insanity, snakebite, and cholera. The purified alkaloid, rauwolfia extract , was isolated in 1952 and is considered the first modern drug for the treatment of hypertension. Reserpine irreversibly binds to the storage vesicles of neurotransmitters, particularly norepinephrine, serotonin and dopamine. Eventually, catecholamine depletion occurs because of the body's inability to store these neurotransmitters. 

3. Function:

1). Reserpine was blocked by adrenergic neurons of antihypertensive drugs. 2). This product is the depletion of peripheral sympathetic nerve endings of adrenaline, heart, brain and other tissues of catecholamines and 5 - HT to anti-high blood pressure, slow heart rate and inhibition of the central nervous system. Antihypertensive effect primarily by reducing cardiac output and reduced peripheral resistance, part of the cardiovascular reflex inhibition to achieve. 3). Reserpine acts on hypothalamic area produce sedation, but no cause drowsiness and anesthetic effects, does not change the sleep EEG, can ease the anxiety of patients with hypertension, tension and headaches. 4). Experimental animal for less than the clinical dose of reserpine, which appears miosis, eyelid wrinkles and sagging, hypothermia, gastrointestinal symptoms such as the acceleration of activity. 

4. Application

Applied in the food field, it has become a new raw material which used in food and beverage industry

Applied in the health product field;

Applied in the pharmaceutical field.