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1 Kilogram |
FOB Price: USD 1.0000 |
80621-81-4 Rifaximin Rifaximin manufacurer
Specification of Rifaximin
ITEMS | SPECIFICATION | RESULTS |
Characters | red- orange to dark red,crystalline powder | red-orange crystalline powder |
Absorption coefficient | 550~610 | 557 |
Identification | ||
1) Chemical | Identification reaction for Ferric chloride, A brownish-black colour is produced | Confirm |
2) HPLC | The retention time of principal peak of substance being examined in the chromatogram obtained in the assay is identical with that of standard solution. | Confirm |
3) IR | The infrared absorption spectrum is concordant with reference spectrum of Rifaximin | Confirm |
Test | ||
1)Crystallinity | Should meet the requirements | Confirm |
2) Loss on drying | Not more than 5.0% | 1.90% |
3) Related substance | Individual impurity not more than 1.5%, | Confirm |
4) Residue on ignition | Total impurities not more than 3.0% | Confirm |
5) Heavy metals | Not more than 0.1% | 0.05% |
6) Abnormal toxicity | Not more than 0.002% | Confirm |
7) Microbial limit tests | Should meet the requirements | Confirm |
Total microbial count | Not more than 1000cfu/g | Confirm |
Mould and Yeast | Not more than100cfu/g | Confirm |
E.coli | Absence per g | Confirm |
Assay | Not less than 98.0% (anhydrous substance). | 99.00% |
Usage for Rifaximin
1) Rifaximin as a gut antibiotic, rifamycin derivatives applicable to acute and chronic intestinal infections caused by Gram-
positive bacteria and negative bacteria, aerobic and anaerobic bacteria, diarrhea syndrome, encephalitis, hepatic coma.
2) Rifaximin Is a highly effective and low toxicity intestinal antibiotics.
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