599-79-1 Salazosulfapyridine sulfasalazine
SULFASALAZINE
CAS: 599-79-1
MF: C18H14N4O5S
MW: 398.4
EINECS: 209-974-3
Mol File: 599-79-1.mol
Sulfasalazine is a sulfa drug, a derivative of mesalazine, and is formed by combining sulfapyridine and salicylate with an azo bond. It may be abbreviated SSZ.
Sulfasalazine is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Effects of SULFASALAZINE
Sulfasalazine is used in the treatment of inflammatory bowel disease, including ulcerative colitis and Crohn's disease. It is also indicated for use in rheumatoid arthritis and used in other types of inflammatory arthritis (e.g. psoriatic arthritis) where it has a beneficial effect. It is often well tolerated compared to other DMARDs.
Items |
Specification |
Identification |
Meet monograph A,B |
Related substances(TLC) |
S.NMT ≤2.0% T.NMT ≤4.0% |
Organic volatile impurities |
Meet the requirements |
Chlorides |
≤0.014% |
Sulphate |
≤ 0.04% |
Heavy metals |
≤ 0.002% |
Loss of drying |
≤ 1.0% |
Sulphated ash |
≤0.5% |
Assay |
97.0%-101.5% |
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