Tamoxifen Citrate

Min.Order / FOB Price:Get Latest Price

1 Metric Ton	FOB Price: USD 1.0000

1 Metric Ton

FOB Price: USD 1.0000

Min.Order :1 Metric Ton
Purity: 99%min
Payment Terms : L/C,D/A,D/P,T/T,

Keywords

54965-24-1 (z)-2-[4-(1,2-diphenyl-1-butenyl)phenoxyl]-n,n-dimethyl-ethanamine-citrate; 1-p-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene citrate 2-{4-[(1E)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate

Quick Details

Appearance:off-white crystalline powder
Application:Metabolism Drug; Carcino-Chemotherapeutic Drug
PackAge:25kg drum
ProductionCapacity:2000|Metric Ton|Year
Storage:Stored in dry and cool place, keeping out of moisture and sunshine, shelf life is two year.
Transportation:by sea,air

Superiority:

Tamoxifen Citrate is a potent and selective inhibitor of PKC (protein kinase C). It is known that Tamoxifen Citrate functions in PKC ε translocation. Studies suggest that Tamoxifen Citrate functions as an estrogen receptor antagonist in breast tissue. Once bound to the estrogen receptor Tamoxifen Citrate will not allow any other ligand to bind to the receptor. In contrast, Tamoxifen Citrate is an agonist towards this receptor in tissues of the endometrium. Studies indicate Tamoxifen Citrate inhibits DNA synthesis and transcription by recruiting co-repressors, which stop estrogen from interacting with genes. When combined with PAX2, Tamoxifen Citrate can inhibit the proliferation of ERBB2. It is also a high affinity activator of the GPR30 receptor. Tamoxifen Citrate is an activator of Estrogen Receptor.

Details:

SPECIFICATION
APPEARANCE	fine off-white crystalline powder
IDENTIFICATION	Complies Test A,B
PURITY	99.0% min (trans-Form 99.0% min + cis-Form 1.0% max)
MELTING POINT	143 - 146 C
RELATED SUBSTANCE	1.0% max
LOSS ON DRYING	0.5% max
RESIDUE ON IGNITION	0.2% max