Thiamphenicol

Min.Order / FOB Price:Get Latest Price

10 Kilogram	FOB Price: USD 1.0000

10 Kilogram

FOB Price: USD 1.0000

Min.Order :10 Kilogram
Purity: 99%min
Payment Terms : L/C,D/A,D/P,T/T

Keywords

15318-45-3 Methylsulfonyl chloramphenicol thiophenicol

Quick Details

Appearance:white or yellowish-white crystalline powder
Application:Antibacterial. D -form as antimicrobial; DL-form in control of fowl cholera.
PackAge:25kg drum
ProductionCapacity:2000|Metric Ton|Year
Storage:sealed and stored in cool places.
Transportation:by sea,air

Superiority:

Introduction

Product Name: Thiamphenicol
CAS: 15318-45-3
MF: C12H15Cl2NO5S
MW: 356.22
EINECS: 239-355-3

Details:

Item	Specifications	Results
Appearance	Fine white or yellowish-white crystalline powder or crystals	Fine white crystalline powder
Identification	According to BP2012	Complies
Light absorption	According to BP2012	Complies
Acidity or alkalinity	According to BP2012	Complies
m.p	163~167℃	165℃
Specific optical rotation	-21°~-24°	-22°
Chloride	≤200ppm	<200ppm
Sulphated ash	≤0.1%	0.05%
Heavy metals	≤10ppm	<10ppm
Loss on drying	≤1.0%	0.02%
Assay	98.0%~100.5%	99.9%

Application

Thiamphenicol (also known as thiophenicol and dextrosulphenidol) is an antibiotic. It is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Like chloramphenicol, it is insoluble in water, but highly soluble in lipids. It is used in many countries as a veterinary antibiotic, but is available in China and Italy for use in humans. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

Thiamphenicol is also widely used in Brazil, particularly for the treatment of sexually transmitted infections and pelvic inflammatory disease.

Unlike chloramphenicol, thiamphenicol is is not readily metabolized in cattle, poultry, sheep, or humans, but is predominantly excreted unchanged. In pigs and rats the drug is excreted both as parent drug and as thiamphenicol glucuronate.

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