157283-68-6 Travoprost (+/-)-16-(M-trifluoromethylphenoxy)Tetranorprostaglandin F2; 15(S)-FLU-IPR
Usage for Travoprost
1) It is also known by the brand names of Travatan and Travatan Z, manufactured by Alcon
2) Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or
ocular hypertension, by reducing intraocular pressure.
3) It is a synthetic prostaglandin analog (or more specifically, an analog of prostaglandin that works by increasing
the outflow of aqueous fluid from the eyes.
Specification of Travoprost USP34
Items |
Specifications |
Results |
Description |
A pale yellow to colorless oil |
A colorless oil |
Identification |
TLC;HPLC |
Complies |
Specific Rotation |
+52°~+58° |
+53.89° |
Water |
≤1.0% |
0.25% |
Related compounds |
Epoxide derivative ≤0.4% 15-epi Diastereomer≤0.1% 5,6-trans Isomer≤3.5% 15-Keto derivative ≤0.3% Any other impurity ≤0.1% Total other impurities ≤1.0% |
Not detectable 0.04% 0.24% 0.07% 0.02% 0.05% |
Residue Solvent |
Isopropanol ≤0.5% Ethyl acetate≤0.25% N-Hexane≤0.029% Ethanol≤0.5% |
0.1% Not detectable Not detectable 0.35% |
Purity by HPLC |
96.0%~102% |
99.61% |
Conclusion |
The results can conform with USP34 |
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