CYCLOPENTOLATE HYDROCHLORIDE C17H26ClNO3 99%
Product Name: CYCLOPENTOLATE HYDROCHLORIDE
Synonyms: N,N-Dimethylaminoethyl-a-(1-Hydroxycyclopentyl)phenylacetate hydrochloride;beta-dimethylaminoethyl(1-hydroxycyclopentyl)phenylacetatehydrochloride;cyclogyl;cyclopentaneaceticacid,1-hydroxy-alpha-phenyl-,2-(dimethylamino)ethylester,;2-(2-(1-hydroxycyclopentyl)-2-phenylacetoxy)ethyldimethylammonium chloride;1-Hydroxy-α-phenylcyclopentane acetic acid, 2-[dimethylamino] ethyl ester hydrochloride;LABOTEST-BB LT00244824;CYCLOPENTOLATE HYDROCHLORIDE
CAS: 5870-29-1
MF: C17H26ClNO3
MW: 327.85
EINECS: 227-521-8
Product Categories: Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File: 5870-29-1.mol
CYCLOPENTOLATE HYDROCHLORIDE Structure
CYCLOPENTOLATE HYDROCHLORIDE Chemical Properties
Melting point 137-141°
storage temp. −20°C
solubility Very soluble in water, freely soluble in ethanol (96 per cent). It shows polymorphism (5.9).
form neat
Safety Information
WGK Germany 2
RTECS GY2450000
HS Code 2922190900
CYCLOPENTOLATE HYDROCHLORIDE Usage And Synthesis
Chemical Properties White Solid
Uses antiviral
Uses antitussive
Uses A mydriatic
Uses Mydriatic;Cholinergic receptor antagonist
Brand name Akpentolate (Akorn); Cyclogyl (Alcon); Pentolair (Bausch & Lomb); Pentolair (Pharmafair).
General Description Cyclopentolatehydrochloride, 2-dimethylaminoethyl 1-hydroxy- -phenylcyclopentaneacetatehydrochloride (Cyclogyl), is a crystalline,white, odorless solid that is very soluble in water,easily soluble in alcohol, and only slightly soluble in ether.A 1% solution has a pH of 5.0 to 5.4.
Cyclopentolate hydrochloride has one half of the antispasmodicactivity of atropine and is nonirritating when instilledrepeatedly into the eye. If not neutralized after the refractionstudies, its effect dissipates within 24 hours. Neutralizationwith a few drops of pilocarpine nitrate solution, 1% to 2%,often results in complete recovery in 6 hours. It is supplied asa ready-made ophthalmic solution in concentrations of either0.5% or 2%.
Clinical Use Cyclopentolate Hydrochloride is used only for its effects on the eye, where it acts asa parasympatholytic. When placed in the eye, it quickly producescycloplegia and mydriasis. Its primary field of usefulnessis in refraction studies. Cyclopentolate hydrochloridecan be used, however, as a mydriatic in the management ofiritis, iridocyclitis, keratitis, and choroiditis. Although itdoes not seem to affect intraocular tension significantly, it isbest to be very cautious with patients with high intraocularpressure and with elderly patients with possible unrecognizedglaucomatous changes.
Product Name: CYCLOPENTOLATE HYDROCHLORIDE
Synonyms: N,N-Dimethylaminoethyl-a-(1-Hydroxycyclopentyl)phenylacetate hydrochloride;beta-dimethylaminoethyl(1-hydroxycyclopentyl)phenylacetatehydrochloride;cyclogyl;cyclopentaneaceticacid,1-hydroxy-alpha-phenyl-,2-(dimethylamino)ethylester,;2-(2-(1-hydroxycyclopentyl)-2-phenylacetoxy)ethyldimethylammonium chloride;1-Hydroxy-α-phenylcyclopentane acetic acid, 2-[dimethylamino] ethyl ester hydrochloride;LABOTEST-BB LT00244824;CYCLOPENTOLATE HYDROCHLORIDE
CAS: 5870-29-1
MF: C17H26ClNO3
MW: 327.85
EINECS: 227-521-8
Product Categories: Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File: 5870-29-1.mol
CYCLOPENTOLATE HYDROCHLORIDE Structure
CYCLOPENTOLATE HYDROCHLORIDE Chemical Properties
Melting point 137-141°
storage temp. −20°C
solubility Very soluble in water, freely soluble in ethanol (96 per cent). It shows polymorphism (5.9).
form neat
Safety Information
WGK Germany 2
RTECS GY2450000
HS Code 2922190900
CYCLOPENTOLATE HYDROCHLORIDE Usage And Synthesis
Chemical Properties White Solid
Uses antiviral
Uses antitussive
Uses A mydriatic
Uses Mydriatic;Cholinergic receptor antagonist
Brand name Akpentolate (Akorn); Cyclogyl (Alcon); Pentolair (Bausch & Lomb); Pentolair (Pharmafair).
General Description Cyclopentolatehydrochloride, 2-dimethylaminoethyl 1-hydroxy- -phenylcyclopentaneacetatehydrochloride (Cyclogyl), is a crystalline,white, odorless solid that is very soluble in water,easily soluble in alcohol, and only slightly soluble in ether.A 1% solution has a pH of 5.0 to 5.4.
Cyclopentolate hydrochloride has one half of the antispasmodicactivity of atropine and is nonirritating when instilledrepeatedly into the eye. If not neutralized after the refractionstudies, its effect dissipates within 24 hours. Neutralizationwith a few drops of pilocarpine nitrate solution, 1% to 2%,often results in complete recovery in 6 hours. It is supplied asa ready-made ophthalmic solution in concentrations of either0.5% or 2%.
Clinical Use Cyclopentolate Hydrochloride is used only for its effects on the eye, where it acts asa parasympatholytic. When placed in the eye, it quickly producescycloplegia and mydriasis. Its primary field of usefulnessis in refraction studies. Cyclopentolate hydrochloridecan be used, however, as a mydriatic in the management ofiritis, iridocyclitis, keratitis, and choroiditis. Although itdoes not seem to affect intraocular tension significantly, it isbest to be very cautious with patients with high intraocularpressure and with elderly patients with possible unrecognizedglaucomatous changes.
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