Doxazosin mesylate Doxazosin mesylate 77883-43-3
Related Substance: |
A ≤0.3% total impurite ≤1.0% |
Loss on Drying: |
≤2.0% |
Residue on Ignition: |
≤0.1% |
Heavy Metal: |
≤10ppm |
Content: |
98.0%~102.0% |
conclusion |
(USP31) (BP2008) |
Usage And Synthesis |
Chemical Properties |
White Crystalline Powder |
Usage |
A selective α-1-adrenergicblocker related to prazosin. |
antihypertensive |
|
Doxazosin is a selective α1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate. |
|
Doxazosin ER is indicated for the treatment of the signs and symptoms of benign prostatic hyperplasia |
|
Biological Activity |
Selective α 1 -adrenoceptor antagonist (pK i values are 9.0, 8.5 and 8.4 for human α 1B , α 1A and α 1D receptors respectively). Displays antihypertensive activity. |
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