High purity Andrographolide with best price and good quality

Product Name:

Andrographolide

Synonyms:

ANDRO;ANDROGRAPHIS;ANDROGRAPHOLIDE;3A,14,15,18-TETRAHYDROXY-5B,9B,H,10A-LAMBDA-8,20-DIENE;2(3H)-FURANONE,3-[2-[(1R,4AS,5R,6R,8AS)-DECAHYDRO-6-HYDROXY-5-(HYDROXYMETHYL)-5,8A-DIMETHYL-2-METHYLENE-1-NAPHTHALENYL]ETHYLIDENE]DIHYDRO-4-HYDROXY-, (3E,4S)-;2(3h)-furanone,3-(2-(decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-met;5-alpha,6-alpha,8a-alpha))-t;hylene-1-naphthalenyl)ethylidene)dihydro-4-hydroxy-,(1r-(1-alpha(e(s*)),4a-be

CAS:

5508-58-7

MF:

C20H30O5

MW:

350.45

Product Categories:

Di-Terpenoids;Asymmetric Synthesis;Chiral Building Blocks;Complex Molecules;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Herb extract;chemical reagent;pharmaceutical intermediate;phytochemical;standardized herbal extract;natural product

Mol File:

5508-58-7.mol

Chemical Properties

melting point 

229-232 °C(lit.)

alpha 

-126 º (c=1.5,HAc)

boiling point 

557.3 °C at 760 mmHg

density 

1.21 g/cm3

flashing point 

195.5 °C

vapor pressure 

9.64E-15 mmHg at 25°C

Usage And Synthesis

Chemical Properties

colorless Plates

Usage

Andrographolide is a labdane diterpenoid. Andrographolide is the main bioactive component isolated from the medicinal plant Andrographis paniculata. Andrographolide showed significant antihepatotoxic action in P. berghei K173- induced hepatic damage in M. natalensis. Andrographolide inhibits tumor necrosis factor-α (TNF-α)-induced intercellular adhesion mol.-1 (ICAM-1) expression and adhesion of HL-60 cells onto human umbilical vein endothelial cells (HUVEC), which are associated with inflammatory diseases. These findings suggest that Andrographolide may have potential as a cardiovascular-protective agent.

antineoplastic