High purity Chloramphenicol with good quality

Product Name:

Chloramphenicol

Synonyms:

,[theta-(theta,theta)]-;[R-(R*,R*)]-2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]ethanamide;2,2-dichloro-n-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-acetamid;2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-,[R-(R*,R*)]-Acetamide;2,2-dichloro-n-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-acetamid;Acetamide, 2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl);Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]-;Acetamide, 2,2-dichloro-N-[beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl]-, D-threo-(-)-

CAS:

56-75-7

MF:

C11H12Cl2N2O5

MW:

323.13

Product Categories:

Active Pharmaceutical Ingredients;Antibiotics for Research and Experimental Use;Biochemistry;Antibiotic Explorer;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;API;Chiral Reagents;Pharmaceutical intermediate;CHLOROMYCETIN;antibiotic

Mol File:

56-75-7.mol

Chemical Properties

melting point 

148-150 °C(lit.)

boiling point 

644.913 °C at 760 mmHg

density 

1.547 g/cm3

alpha 

19.5 º (c=6, EtOH)

refractive index 

20 ° (C=5, EtOH)

Fp 

14 °C

storage temp. 

2-8°C

Water Solubility 

2.5 g/L (25 º C)

Chemical Properties

White to grey-white crystalline powder

Usage

antibacterial, antirickettsial, inhibits protein synthesis

Chloramphenicol is unusual nitroaromatic metabolite produced by Streptomyces venezuelae, first published in 1947. Chloramphenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Although restricted to ocular use, antibiotic resistance to other classes has refocused attention on this class. Chloramphenicol acts by binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis. Chloramphenicol has been extensively studied with over 35,000 literature citations.

Broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and gram-negative bacteria. Antibacterial; antirickettsial

Storage and transportation characteristics

Warehouse ventilation drying.

Fire extinguishing agent

Dry powder, foam, carbon dioxide